Results 101 to 110 of about 5,251,416 (217)

Plasmablasts and neuroimmunological disorders

open access: yesImmunological Medicine, 2019
Neuroimmunological disorders are diseases of the nervous system, wherein the immune system contributes to tissue injury and repair. Autoantibodies are useful biomarkers for the diagnosis of neuroimmunological disorders and evaluating disease activity ...
Norio Chihara   +2 more
doaj   +1 more source

Immunotherapy for B-Cell Neoplasms using T Cells expressing Chimeric Antigen Receptors : From antigen choice to clinical implementation

open access: yesSultan Qaboos University Medical Journal, 2012
Immunotherapy with T cells expressing chimeric antigen receptors (CAR) is being evaluated as a potential treatment for B-cell neoplasms. In recent clinical trials it has shown promising results.
Mohamed-Rachid Boulasse, Ahmed Galal
doaj  

Morphologic observations of human T and B lymphocytes by scanning electron microscopy

open access: yes, 1974
T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core   +1 more source

Differential expression of CD 180 and IgM by B-cell chronic lymphocytic leukaemia cells using mutated and unmutated immunoglobulin VH genes

open access: yes, 2005
We have studied the surface expression of the Toll-like receptor family member CD180 on cells from 78 patients with B-chronic lymphocytic leukaemia (B-CLL). B-CLL cells had variable levels of CD180 expression, but this was always less than that expressed
Jewell, A.P.   +26 more
core   +1 more source

IgE+ B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis

open access: yes, 2015
Background Despite the critical role of immunoglobulin E (IgE) in allergy, circulating IgE+ B cells are scarce. Here, we describe in patients with allergic rhinitis B cells with a memory phenotype responding to a prototypic aeroallergen.
Wong, K.J   +11 more
core   +1 more source

Expansion of CD4+ T cells with a cytotoxic phenotype in patients with B-chronic lymphocytic leukaemia (B-CLL)

open access: yes, 2001
Abnormal CD4/CD8 ratios and T-cell function have previously been shown in patients with B-chronic lymphocytic leukaemia (B-CLL). We have demonstrated that CD4+ T cells containing both serine esterase and perforin (PF) are increased in the blood of these ...
Roschupkina, T.   +7 more
core   +1 more source

B-cell kinetics in humans: rapid turnover of peripheral blood memory cells.

open access: yes, 2005
Information about the kinetic behavior and lifespan of lymphocytes is crucial to understanding the mechanisms that regulate processes such as immunologic memory. We have used in vivo labeling of dividing cells with 6,6-(2)H(2)-glucose, combined with cell
Wallace, Diana L   +33 more
core   +1 more source

An antigen-driven B-cell response within the salivary glands of patients with Sjögren’s syndrome [PDF]

open access: yes, 2002
Infection with a bacterium or virus induces the production of antibodies, specialised protein molecules that bind to and eliminate the microorganism.
Berek, C., Stott, D.I.
core  

Long-term follow-up of patients with refractory systemic lupus erythematosus during rituximab treatment

open access: yesТерапевтический архив, 2014
AIM: To evaluate the impact of anti-B-cell therapy on the clinical and immunological parameters of systemic lupus erythematosus (SLE) activity, on the time course of changes in these parameters during long-term follow-up, and on the tolerability of ...
M É Tsanian   +7 more
doaj  

Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells

open access: yes
Interferon (IFN)-α is the earliest cytokine signature observed in individuals at risk for type 1 diabetes (T1D), but the effect of IFN-α on the antigen repertoire of HLA Class I (HLA-I) in pancreatic β-cells is unknown.
Z Zhou (7793243)   +29 more
core  

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