Results 41 to 50 of about 5,251,416 (217)

DETERMINING REFERENCE RANGES FOR TREC AND KREC ASSAYS IN IMMUNE DEFICIENCY SCREENING OF NEWBORNS IN RUSSIAN FEDERATION

open access: yesМедицинская иммунология, 2019
In this work, we used a reference population of newborns and sampled dried blood spots on Guthrie cards of 2,739 individual samples to determine the reference intervals for TRECs and KRECs values, in order to diagnose primary immunodeficiency by means of
M. A. Gordukova   +6 more
doaj   +1 more source

Structural Analysis of Avian Encephalomyelitis Virus Polyprotein for Development of Multi Epitopes Vaccine Using Immunoinformatics Approach

open access: yesJournal of Pure and Applied Microbiology, 2021
Avian Encephalomyelitis (AE) is the disease caused by avian encephalomyelitis virus (AEV). The disease mainly affects young birds nervous system worldwide causing high morbidity and variable mortality rate in chicks and noticed egg dropping and ...
Fatima Khalid Elhassan   +4 more
doaj   +1 more source

Versatility of megakaryocytes in homeostasis and disease

open access: yesBlood Science
Megakaryocytes (MKs) constitute a small portion of bone marrow cells and are primarily responsible for producing platelets, which are essential for hemostasis and wound healing.
Daosong Wang, Jiayi Xie, Meng Zhao
doaj   +1 more source

Antibodies: what makes us stronger

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Neutralizing antibodies are the basis of almost all approved prophylactic vaccines and the foundation of effective protection from pathogens, including the recently emerging SARS Coronavirus 2 (SARS-CoV-2).
Natalia T. Freund
doaj   +1 more source

Selenium supplementation suppresses immunological and serological features of lupus in B6.Sle1b mice

open access: yesAutoimmunity, 2019
Systemic lupus erythematosus (SLE) is a debilitating multi-factorial immunological disorder characterized by increased inflammation and development of anti-nuclear autoantibodies.
Chetna Soni   +5 more
doaj   +1 more source

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation [PDF]

open access: yes, 1993
We have constructed a soluble chimeric fusion protein between the mouse CD8 alpha chain and the mouse CD40 T cell ligand. This protein binds to both human and mouse B cells.
Lane, P.   +11 more
core   +1 more source

Yellow fever virus vaccination: an emblematic model to elucidate robust human immune responses

open access: yesHuman Vaccines & Immunotherapeutics, 2021
By preventing infectious diseases, vaccines contribute substantially to public health. Besides, they offer great opportunities to investigate human immune responses. This is particularly true for live-attenuated virus vaccines which cause resolving acute
Amandine Bovay   +2 more
doaj   +1 more source

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells.

open access: yes, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T.   +12 more
core   +1 more source

Regulation of murine B cell development and function [PDF]

open access: yes, 2011
Vertebrates have developed an effective and protective, yet complex and dynamic immune system to defend themselves against the many threats from microorganisms.
Flück, Lukas Andreas
core   +1 more source

Features of B cell subsets in primary Sjogren’s syndrome and systemic lupus erythematosus

open access: yesНаучно-практическая ревматология
Background. Lymphocyte subsets in autoimmune diseases, such as systemic lupus erythematosus (SLE) and primary Sjogren’s syndrome (pSS), have been intensively studied in recent years.
S. S. Benevolenskaya   +13 more
doaj   +1 more source

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