Results 21 to 30 of about 5,251,416 (217)

Clinical case of primary immunodeficiency: X-linked agammaglobulinemia

Медицинская иммунология, 2020
Aclinical case ofprimary immunodeficiency state (PIDS) is described: X-linked agammaglobulinemia in the boy of 8 years old. The results of molecular genetic studies: gene btk (ex 1-19) genome version GRCh38.p5, transcript version ENST00000308731 single ...
E. V. Kuvschinova, L. M. Kurtasova, A. G. Borisov, A. R. Schmidt, T. A. Gerasimova   +4 more
doaj   +1 more source

Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection. [PDF]

, 2011
BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype.
Low, Jenny G., Bela-Ong, D.B., Gu, F., Martin L. Hibberd, Fink, Katja, Mickey B Koh, Hibberd, Martin, L, Martin L Hibberd, Katja Fink, Ooi Eng Eong, Leo Yee Sin, Toh, Ying, Xiu, Balakrishnan, Thavamalar, Jenny G Low, Leo, Yee Sin, Balakrishnan, T., Devi, S., Toh Ying Xiu, Dennis B Bela-Ong, Marie Flamand, Flamand, M., Hibberd, Martin L., Flamand, Marie, Leo, Y.S., Flamand Marie, Devi Shamala, Bela-Ong, Dennis, B, Thavamalar Balakrishnan, Yee Sin Leo, Fink Katja, Fink, K., Hibberd, M.L., Jenny G. Low, Ying Xiu Toh, Ooi, E.E., Toh, Y.X., Gu Feng, Ooi, Eng, Eong, Leo, Yee, Sin, Koh, Mickey B., Hibberd Martin L., Bela-ong, Dennis B., Koh, Mickey, B, Eng Eong Ooi, Feng Gu, Low, J.G., Dennis B. Bela-Ong, Balakrishnan Thavamalar, Low, Jenny G, Low Jenny G., Shamala Devi, Toh, Ying Xiu, Bela-Ong, Dennis B, Low, Jenny, G, Mickey B. Koh, Koh Mickey B., Devi, Shamala, Ooi, Eng Eong, Hibberd, Martin L, Koh, M.B., Bela-Ong Dennis B., Koh, Mickey B, Gu, Feng   +62 more
core   +1 more source

Unique B cell responses in B cell-dependent and B cell-independent EAE

Autoimmunity, 2011
Previous studies characterized B cell-dependent and B cell-independent models of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. To further characterize the B cell response generated in these two models, the serum antibody response and the B cell surface immunoglobulin (Ig) repertoire were analyzed following immunization of wild-type ...
Guorong, Liu, Kamaldeen A, Muili, Vrushali V, Agashe, Jeri-Anne, Lyons   +3 more
openaire   +2 more sources

The B cell receptor, but not the pre-B cell receptor, mediates arrest of B cell differentiation [PDF]

European Journal of Immunology, 2000
B cell development in organ cultures of fetal liver from mice at day 14 of gestation resembles in kinetics and cell numbers generated the one observed in vivo. This development in vitro can be blocked by an IL-7 receptor-specific monoclonal antibody. Monoclonal antibodies specific for the pre-B cell receptor, i. e. for VpreB, lambda5, or muH chains, do
R, Ceredig, A G, Rolink, F, Melchers, J, Andersson   +3 more
openaire   +2 more sources

Immunomodulatory Treatment Strategies Targeting B Cells for Heart Failure

Frontiers in Pharmacology, 2022
Cardio-oncology, a nascent specialty, has evolved as a concerted strategy to address the cardiovascular complications of cancer therapies. On the other hand, emerging evidence has shown that some anti-tumor drugs, such as CD20-targeted rotuximab, also ...
Xinxin Zhang, Yuxi Sun, Ning Wang, Yanli Zhang, Yunlong Xia, Ying Liu   +5 more
doaj   +1 more source

Detection of IL-10 in Murine B Cells: In Vitro and In Vivo Techniques

, 2021
With the ever-increasing understanding of the roles of B cells in immune response and autoimmune pathogenesis, various techniques have been optimized for the detection of IL-10 production in B cells.
Wang, X, Xiang Lin, Lin, X, Lu, L, Xiaohui Wang, Liwei Lu   +5 more
core   +1 more source

B cells and cancer [PDF]

Cancer Cell, 2021
Tumor-infiltrating B cells complement T cell-mediated antitumor immunity. A panel of experts share their views on the complexity of B cells within the tumor microenvironment, the variety of mechanisms by which these cells control tumor growth, their organization in tertiary lymphoid structures, and their association with immunotherapy response.
Engelhard, Victor, Conejo-Garcia, Jose R, Ahmed, Rafi, Nelson, Brad H, Willard-Gallo, Karen, Bruno, Tullia C, Fridman, Wolf Herman   +6 more
openaire   +2 more sources

Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes [PDF]

, 2013
Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the
Cols, M, Cerutti, A, Andrea Cerutti, Puga, I, Montserrat Cols, Irene Puga   +5 more
core   +1 more source

B cells and autoimmunity [PDF]

Current Opinion in Immunology, 2011
There is a growing appreciation for the role for B cells in autoimmune disorders in which inflammation is driven by T cells, in addition to the well-established role for B cells in autoimmune disorders characterized by pathogenic auto-antibodies. Current information on tolerance checkpoints in B cells, B cell depletion, BAFF blockade, regulatory B ...
Shiv, Pillai, Hamid, Mattoo, Annaiah, Cariappa   +2 more
openaire   +2 more sources

The composition of peripheral immunocompetent cell subpopulations and cytokine content in the brain structures of mutant Disc1-Q31L mice

Вавиловский журнал генетики и селекции, 2020
The DISC1 (disrupted in sсhizophrenia 1) gene is associated with brain dysfunctions, which are involved in a variety of mental disorders, such as schizophrenia, depression and bipolar disorder.
M. M. Gevorgyan, S. Ya. Zhanaeva, E. L. Alperina, T. V. Lipina, G. V. Idova   +4 more
doaj   +1 more source