Results 271 to 280 of about 29,942,317 (406)

Super-silencers are crucial for development and carcinogenesis in B cells. [PDF]

Nat Commun
Huang D, Petrykowska HM, Kumar D, Kardava L, Moir S, Afzali B, Elnitski L, Ovcharenko I.   +7 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The Increased Secretion of Lactate Observed in Obesity and Aging Leads to the Generation of Pathogenic B Cells. [PDF]

Eur J Immunol
Romero M, Virtue A, Miller K, Gelsomini A, Suresh D, LaPointe S, Pallikkuth S, Frasca D.   +7 more
europepmc   +1 more source

Enteric bacteria promote human and mouse norovirus infection of B cells

Science, 2014
Melissa K. Jones, Makiko Watanabe, Shu Zhu, Christina L. Graves, Lisa R. Keyes, Katrina R. Grau, M. González-Hernández, N. M. Iovine, C. Wobus, J. Vinjé, S. Tibbetts, Shannon M. Wallet, Stephanie M. Karst   +12 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Pentanoate modulates B cells to suppress allergic contact hypersensitivity. [PDF]

Sci Rep
Alhmoudi S, Kader HA, Alia K, Shiek SS, Saraswathiamma D, Sugathan S, Waheed Y, Karam SM, Dhaheri YA, Muhammad K.   +9 more
europepmc   +1 more source

Diffuse large B – Cell lymphoma involving the maxilla in a minor [PDF]

, 2014
Garish Kumar
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Stratification of systemic lupus erythematosus with IGHV4-34 in unswitched memory B cells. [PDF]

Rheumatology (Oxford)
Ushijima TS, Teruya H, Abe T, Itamiya T, Ota M, Okamura T, Fujio K.   +6 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source