Results 21 to 30 of about 8,044,473 (306)

Clinical case of primary immunodeficiency: X-linked agammaglobulinemia

open access: yesМедицинская иммунология, 2020
Aclinical case ofprimary immunodeficiency state (PIDS) is described: X-linked agammaglobulinemia in the boy of 8 years old. The results of molecular genetic studies: gene btk (ex 1-19) genome version GRCh38.p5, transcript version ENST00000308731 single ...
E. V. Kuvschinova   +4 more
doaj   +1 more source

Prognostic Impact of Circulating CD28 Negative Suppressor T Cells and Memory B Cells on Treatment Outcomes of Patients with Breast Cancer [PDF]

open access: yesIranian Journal of Immunology, 2020
Background: It has been suggested that routine assessment and quantification of different lymphocyte subsets can provide clinically meaningful prognostic information in breast cancer (BC). Objective: To determine the relationship between peripheral blood
Asmaa Zahran   +6 more
doaj   +1 more source

Acute disruption of bone marrow B lymphopoiesis and apoptosis of transitional and marginal zone B cells in the spleen following a blood-stage Plasmodium chabaudi infection in mice [PDF]

open access: yes, 2011
B cells and antibodies are essential for the protective immune response against a blood-stagePlasmodiuminfection. Although extensive research has focused on memory as well as plasma B-cell responses during infection, little is known about how malaria ...
Bockstal, Viki   +2 more
core   +2 more sources

Regulation of B cell fate by chronic activity of the IgE B cell receptor. [PDF]

open access: yes, 2016
IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE+ B cells are constrained by chronic activity of the IgE B cell receptor (BCR).
Allen, Christopher DC   +6 more
core   +1 more source

The composition of peripheral immunocompetent cell subpopulations and cytokine content in the brain structures of mutant Disc1-Q31L mice

open access: yesВавиловский журнал генетики и селекции, 2020
The DISC1 (disrupted in sсhizophrenia 1) gene is associated with brain dysfunctions, which are involved in a variety of mental disorders, such as schizophrenia, depression and bipolar disorder.
M. M. Gevorgyan   +4 more
doaj   +1 more source

Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms. [PDF]

open access: yes, 2018
Many patients with B-cell malignancies can be successfully treated, although tumor eradication is rarely achieved. T-cell-directed killing of tumor cells using engineered T-cells or bispecific antibodies is a promising approach for the treatment of ...
Aliberti S   +24 more
core   +1 more source

Stem Cell Ophthalmology Treatment Study (SCOTS): Bone Marrow-Derived Stem Cells in the Treatment of Age-Related Macular Degeneration

open access: yesMedicines, 2020
Background: Dry age-related macular degeneration (AMD) is one of the leading causes of vision loss in older patients. The macula accumulates drusen with loss of retinal pigment epithelial cells and photoreceptors.
Jeffrey N. Weiss, Steven Levy
doaj   +1 more source

SUPERANTIGENS

open access: yesActa Agriculturae Slovenica, 1998
Superantigens are bacterial, viral, retroviral and some naturally occurring proteins that can specifically activate a large proportion of T and/or B cells.
Mojca NARAT
doaj   +1 more source

B-cell Tolerance

open access: yesTransplantation, 2006
Autoreactive B cells are actively tolerized to more abundant self-antigens by a series of checkpoints involving receptor editing, deletion, anergy and competition for growth factors. In contrast, B cells reactive against rare, sequestered or tissue specific self-antigens remain functionally naïve.
Ferry, H   +6 more
openaire   +3 more sources

Characterization of B1-cells during experimental leukomogenesis

open access: yesВопросы вирусологии, 2020
Background. Bovine leukemia causes a significant polyclonal expansion of CD5+ , IgM+ B lymphocytes, known as persistent lymphocytosis (PL), in approximately 30% of infected cattle.
I. Yu. Ezdakova   +3 more
doaj   +1 more source

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