Results 11 to 20 of about 70 (64)
Experimental Biology and Medicine, 1991 SummaryA major proportion of CD5+ B lymphocytes are committed to the production of a discrete type of antibody that is polyreactive. Polyreactive antibodies appear to use selected V and, perhaps, D gene segments, mostly in unmutated configuration. They generally display relatively low affinity for different antigens and are often part of the primary ...
M T, Kasaian, H, Ikematsu, P, Casali
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Japanese Journal of Clinical Immunology, 2005 Recent studies have revealed that B cells play a critical role in autoimmunity and disease expression through various functions, including autoantibody production, cytokine secretion, antigen presentation, and co-stimulatory effect. Selective targeting of B cells has been recently achieved using a chimeric monoclonal antibody against CD20 (Rituximab ...
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B‐lymphocyte calcium inFlux [PDF]
Immunological Reviews, 2009 Summary: Dynamic changes in cytoplasmic calcium concentration dictate the immunological fate and functions of lymphocytes. During the past few years, important details have been revealed about the mechanism of store‐operated calcium entry in lymphocytes, including the molecular identity of calcium release‐activated calcium (CRAC) channels and the ...
Leslie B, King, Bruce D, Freedman
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Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 2016 The B cell development from hematopoietic stem cells is a continuous and highly regulated process where multiple differentiation potentials are gradually lost while acquiring lineage specialized functions. At 50 years of the B cell discovery, the current knowledge of its early differentiation largely derive from the isolation and characterization of ...
Juan Carlos Balandrán +1 more
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Peripheral B lymphocyte tolerance
The Keio Journal of Medicine, 2004 This lecture discusses two interrelated topics, B cell tolerance in the peripheral immune system and BAFF. Using the 3-83 antibody transgenic mouse bred to mice carrying cognate antigen in the liver, we previously found that clonal elimination drastically reduced the precursor frequency of autoreactive cells.
Amanda, Gavin +8 more
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Citation: 'B lymphocyte' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12937 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Immunology Today, 1983
B lymphocytes are exceptionally diverse, partly because different clones have membrane receptors with specificities for different antigens and partly because the cells exist in a series of distinct differentiation states and may constitute more than a single cellular lineage.
J T, Kung, W E, Paul
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B lymphocytes are exceptionally diverse, partly because different clones have membrane receptors with specificities for different antigens and partly because the cells exist in a series of distinct differentiation states and may constitute more than a single cellular lineage.
J T, Kung, W E, Paul
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Immunology Today, 1983
B cells can influence an immune response in an antigen-specific manner by generating antibody which shuts down the response through negativefeedback. But there is growing evidence that B cells can also act upon antibody production as non-specific suppressor cells.
K M, Gilbert, M K, Hoffmann
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B cells can influence an immune response in an antigen-specific manner by generating antibody which shuts down the response through negativefeedback. But there is growing evidence that B cells can also act upon antibody production as non-specific suppressor cells.
K M, Gilbert, M K, Hoffmann
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Immunology Today, 1981
A review focussing on the lessons learned from polyclonal activation of B cells.
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A review focussing on the lessons learned from polyclonal activation of B cells.
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