Results 161 to 170 of about 26,623 (217)

Screening and experimental validation of modified Gandou Decoction-targeted inhibitors for alleviating AD components via network pharmacology, machine learning, and molecular dynamics simulation. [PDF]

Front Pharmacol
Ye S, Zhang S, Zhang L, Peng G, Xie M, Huang X, Hu Y.   +6 more
europepmc   +1 more source

Glycyrrhizic Acid Attenuates Aβ₄₂-Induced Neurodegeneration Through Coordinated Regulation of Oxidative Stress, Synaptic Markers, and Key Alzheimer's Signaling Pathways. [PDF]

Cells
Amrutha S, Prasad TSK, Modi PK.
europepmc   +1 more source

Cross-Species Aging Knowledge Integration into Agentic AI Platform Uncovers Conserved Mechanisms

Ahuja G, Sharma A, Singh A, Kedia S, Sharma A, Gautam V, Sharma P, Khandelwal A, Ramakrishna S, Muddashetty R, Freude K, Solanki S, Chauhan S, Kumar S, Satija S, Duari S, Arora S, Gupta A, Shome R, Sengupta D, nair D.   +20 more
europepmc   +1 more source

APP SUMOylation prevents BACE1 cleavage of APP and increases BACE1 degradation to promote the nonamyloidogenic pathway. [PDF]

Mol Med
Liu YC, Hsu WL, Ma YL, Yin CY, Cheng KM, Lee EHY.   +5 more
europepmc   +1 more source

Putative long range mossy fiber sprouting and regional cytochrome c oxidase alteration in the hippocampus of patients with mesial temporal lobe epilepsy. [PDF]

Sci Rep
Tu T, Wan L, Zhang QL, Yang C, Zhou HS, Sun ZP, Long HY, Tang BS, Pan A, Tu E, Wang J, Yang ZQ, Li ZY, Yan XX.   +13 more
europepmc   +1 more source

Modeling amyloid plaque turnover dynamics improves characterization of drug effects. [PDF]

Alzheimers Dement (N Y)
van Maanen E, Robey S, Bennacef I, Duffull S, Egan MF, Kennedy ME, Stone JA.   +6 more
europepmc   +1 more source