Results 201 to 210 of about 26,623 (217)

NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models

Proceedings of the National Academy of Sciences of the United States of America, 2019
Gahee Bahn, Yuri Choi, Jin Su Park
exaly  

Targeting the β secretase BACE1 for Alzheimer's disease therapy

Lancet Neurology, The, 2014
Riqiang Yan, Robert Vassar
exaly  

BACE1 Physiological Functions May Limit Its Use as Therapeutic Target for Alzheimer's Disease

Trends in Neurosciences, 2016
Soraia Barao, Stefan F Lichtenthaler, Bart De Strooper   +2 more
exaly  

Synthesis of a BACE1 Inhibitor

Synfacts, 2013
  +4 more sources

Bace1 modulates myelination in the central and peripheral nervous system

Nature Neuroscience, 2006
Xiangyou Hu, Caitlin W Hicks, Wendy B Macklin   +2 more
exaly  

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

EMBO Journal, 2013
Cyril Cheret, Michael Willem, Hagen Wende   +2 more
exaly  

BACE1 is the major β-secretase for generation of Aβ peptides by neurons

Nature Neuroscience, 2001
Huaibin Cai
exaly  

Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

Nature Neuroscience, 2001
Martin Citron, Robert Vassar
exaly  

Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease

Journal of Controlled Release, 2018
Peng Yang, Wei Lu, Qizhi Zhang
exaly  

Boom in the development of non‐peptidic β‐secretase (BACE1) inhibitors for the treatment of Alzheimer's disease

Medicinal Research Reviews, 2009
Romano Silvestri
exaly