Transaldolase in Bacillus methanolicus: biochemical characterization and biological role in ribulose monophosphate cycle [PDF]
BMC Microbiology, 2020 Background The Gram-positive facultative methylotrophic bacterium Bacillus methanolicus uses the sedoheptulose-1,7-bisphosphatase (SBPase) variant of the ribulose monophosphate (RuMP) cycle for growth on the C1 carbon source methanol.
Johannes Pfeifenschneider +4 more
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Establishment of a functional system for recombinant production of secreted proteins at 50 °C in the thermophilic Bacillus methanolicus [PDF]
Microbial Cell Factories, 2020 Background The suitability of bacteria as microbial cell factories is dependent on several factors such as price of feedstock, product range, production yield and ease of downstream processing.
Marta Irla +3 more
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Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The use of methanol as carbon source for biotechnological processes has recently attracted great interest due to its relatively low price, high abundance, high purity, and the fact that it is a non-food raw material.
Luciana Fernandes Brito +6 more
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Characterization of D-Arabitol as Newly Discovered Carbon Source of Bacillus methanolicus [PDF]
Frontiers in Microbiology, 2019 Bacillus methanolicus is a Gram-positive, thermophilic, methanol-utilizing bacterium. As a facultative methylotroph, B. methanolicus is also known to utilize D-mannitol, D-glucose and, as recently discovered, sugar alcohol D-arabitol.
Marina Gil López +5 more
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Corrigendum: Genome-Based Genetic Tool Development for Bacillus methanolicus: Theta- and Rolling Circle-Replicating Plasmids for Inducible Gene Expression and Application to Methanol-Based Cadaverine Production [PDF]
Frontiers in Microbiology, 2019 © 2019 Irla, Heggeset, Nærdal, Paul, Haugen, Le, Brautaset and Wendisch. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Marta Irla +8 more
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Enhanced Glutamate Synthesis and Export by the Thermotolerant Emerging Industrial Workhorse Bacillus methanolicus in Response to High Osmolarity [PDF]
Frontiers in Microbiology, 2021 The thermotolerant methylotroph Bacillus methanolicus MGA3 was originally isolated from freshwater marsh soil. Due to its ability to use methanol as sole carbon and energy source, B.
Christine Frank +6 more
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Metabolic engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol [PDF]
Microbial Biotechnology, 2023 The growing need of next generation feedstocks for biotechnology spurs an intensification of research on the utilization of methanol as carbon and energy source for biotechnological processes.
Vivien Jessica Klein +4 more
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Genomic and Transcriptomic Investigation of the Physiological Response of the Methylotroph Bacillus methanolicus to 5-Aminovalerate [PDF]
Frontiers in Microbiology, 2021 The methylotrophic thermophile Bacillus methanolicus can utilize the non-food substrate methanol as its sole carbon and energy source. Metabolism of L-lysine, in particular its biosynthesis, has been studied to some detail, and methanol-based L-lysine ...
Carsten Haupka +4 more
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Charting the Metabolic Landscape of the Facultative Methylotroph
mSystems, 2020 Bacillus methanolicus MGA3 is a thermotolerant and relatively fast-growing methylotroph able to secrete large quantities of glutamate and lysine. These natural characteristics make B.
Baudoin Delépine +5 more
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Production of Value-Added Chemicals by Bacillus methanolicus Strains Cultivated on Mannitol and Extracts of Seaweed Saccharina latissima at 50°C [PDF]
Frontiers in Microbiology, 2020 The facultative methylotroph Bacillus methanolicus MGA3 has previously been genetically engineered to overproduce the amino acids L-lysine and L-glutamate and their derivatives cadaverine and γ-aminobutyric acid (GABA) from methanol at 50°C.
Sigrid Hakvåg +5 more
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