Results 51 to 60 of about 664 (136)

Upregulated transcription of plasmid and chromosomal ribulose monophosphate pathway genes is critical for methanol assimilation rate and methanol tolerance in the methylotrophic bacterium Bacillus methanolicus. [PDF]

J Bacteriol, 2006
Jakobsen ØM, Benichou A, Flickinger MC, Valla S, Ellingsen TE, Brautaset T.   +5 more
europepmc   +3 more sources

Leveraging substrate flexibility and product selectivity of acetogens in two‐stage systems for chemical production

Microbial Biotechnology, Volume 16, Issue 2, Page 218-237, February 2023., 2023
Carbon dioxide recycling is a compelling need and microbial carbon dioxide fixation in value‐added compounds is a valuable opportunity. Fermentation of CO2 gas streams using acetogenic bacteria is consolidating as a key biotechnology to move toward a cyclic carbon economy.
Luca Ricci, Arne Seifert, Sebastien Bernacchi, Debora Fino, Candido Fabrizio Pirri, Angela Re   +5 more
wiley   +1 more source

Development and application of CRISPR‐based genetic tools in Bacillus species and Bacillus phages

Journal of Applied Microbiology, Volume 133, Issue 4, Page 2280-2298, October 2022., 2022
Abstract Recently, the clustered regularly interspaced short palindromic repeats (CRISPR) system has been developed into a precise and efficient genome editing tool. Since its discovery as an adaptive immune system in prokaryotes, it has been applied in many different research fields including biotechnology and medical sciences.
Yafeng Song, Siqi He, Anita Jopkiewicz, Rita Setroikromo, Ronald van Merkerk, Wim J. Quax   +5 more
wiley   +1 more source

Efficient cell factories for the production of N‐methylated amino acids and for methanol‐based amino acid production

Microbial Biotechnology, Volume 15, Issue 8, Page 2145-2159, August 2022., 2022
Methanol is a reduced form of carbon dioxide that can be utilized by methylotrophic microorganisms. In this review, we review on how this feedstock, that does not have competing uses in food or feed, serves amino acid fermentation processes. Summary The growing world needs commodity amino acids such as L‐glutamate and L‐lysine for use as food and feed,
Marta Irla, Volker F. Wendisch
wiley   +1 more source

Integrating greenhouse gas capture and C1 biotechnology: a key challenge for circular economy

Microbial Biotechnology, Volume 15, Issue 1, Page 228-239, January 2022., 2022
State of the art on the valorisation of C1 carbon sources obtained either from natural or anthropogenic origins as a key challenge for the circular economy.
José L. García, Beatriz Galán
wiley   +1 more source

Genome Sequence of Thermotolerant Bacillus methanolicus: Features and Regulation Related to Methylotrophy and Production of l -Lysine and l -Glutamate from Methanol [PDF]

Applied and Environmental Microbiology, 2012
Tonje Marita Bjerkan Heggeset, Alexander Wentzel, Trygve Brautaset   +2 more
exaly   +2 more sources

Charting the Metabolic Landscape of the Facultative Methylotroph Bacillus methanolicus

mSystems, 2020
Bacillus methanolicus MGA3 is a thermotolerant and relatively fast-growing methylotroph able to secrete large quantities of glutamate and lysine. These natural characteristics make B.
Baudoin Delépine, Marina Gil López, Marc Carnicer, Cláudia M. Vicente, Volker F. Wendisch, Stéphanie Heux   +5 more
doaj   +1 more source

Metabolic engineering of microorganisms for the production of multifunctional non‐protein amino acids: γ‐aminobutyric acid and δ‐aminolevulinic acid

Microbial Biotechnology, Volume 14, Issue 6, Page 2279-2290, November 2021., 2021
For the first time, we put GABA and ALA together for a detailed summary, analysis and comparison, and put forward further strategies to meet the challenges of industrial competition strains. Summary Gamma‐aminobutyric acid (GABA) and delta‐aminolevulinic acid (ALA), playing important roles in agriculture, medicine and other fields, are multifunctional ...
Anping Su, Qijun Yu, Ying Luo, Jinshui Yang, Entao Wang, Hongli Yuan   +5 more
wiley   +1 more source

Strategies and challenges with the microbial conversion of methanol to high‐value chemicals

Biotechnology and Bioengineering, Volume 118, Issue 10, Page 3655-3668, October 2021., 2021
Methanol is considered as one promising alternative substrate for cell refinery, owing to its availability from a variety of sources (CO2, petroleum, nature gas, coal). Here we present a detailed analysis of methanol metabolic pathways from different methylotrophs.
Chunjun Zhan, Xiaowei Li, Yankun Yang, Jens Nielsen, Zhonghu Bai, Yun Chen   +5 more
wiley   +1 more source

Transcriptome analysis reveals the roles of nitrogen metabolism and sedoheptulose bisphosphatase pathway in methanol‐dependent growth of Corynebacterium glutamicum

Microbial Biotechnology, Volume 14, Issue 4, Page 1797-1808, July 2021., 2021
Transcriptome analysis of methanol‐dependent Corynebacterium glutamicum reveals metabolic regulation changes in central metabolism. It is experimentally verified that nitrate could serve as an additional electron acceptor for aerobic methanol metabolism and the biosynthesis of several amino acids limits methylotrophic growth, and the SBPase variant for
Liwen Fan, Yu Wang, Jin Qian, Ning Gao, Zhihui Zhang, Xiaomeng Ni, Letian Sun, Qianqian Yuan, Ping Zheng, Jibin Sun   +9 more
wiley   +1 more source