Results 81 to 90 of about 281,344 (286)
, 2012 We analyze how functionality could be obtained within single-molecule devices by using a combination of non-equilibrium Green's functions and ab-initio calculations to study the inelastic transport properties of single-molecule junctions.
Dash, L. K. +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BINOL as a chiral element in mechanically interlocked molecules
Beilstein Journal of Organic Chemistry, 2022 In this minireview we present the use of the axially chiral 1,1'-binaphthyl-2,2'-diol (BINOL) unit as a stereogenic element in mechanically interlocked molecules (MIMs).
Matthias Krajnc, Jochen Niemeyer
doaj +1 more source
Effects of sulfonation process on thermal behavior and microstructure of sulfonated polysulfone membranes as a material for Proton Exchange Membrane (PEM) [PDF]
, 2004 This paper reports the effect of sulfonation processon thermal behavior and microstrucutre of sulfonated polysulfone membrane. Various degree of sulfonation reactin has been conducted and the sulfonated membranes were characterized by thermal gravimetric
Ismail, A. F., Naim, R., Saidi, H.
core
Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse Agonist [PDF]
ACS Chemical Biology, 2016 A backbone-modified peptide derived from parathyroid hormone (PTH) is shown to function as an inhibitor and inverse agonist of parathyroid hormone receptor-1 (PTHR1) signaling. This receptor acts to regulate calcium and phosphate homeostasis, as well as bone turnover and development.
Ross W, Cheloha +4 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Beilstein Journal of Organic ChemistryWe present a new class of tunable aryl alkyl ionic liquids (TAAILs) based on 1-aryl-4,5-dimethylimidazolium cations with electron-withdrawing and -donating substituents in different positions of the phenyl ring and the bis(trifluoromethylsulfonyl)imide ...
Stefan Fritsch, Thomas Strassner
doaj +1 more source
A C35 Carotenoid Biosynthetic Pathway [PDF]
, 2003 Upon coexpression with Erwinia geranylgeranyldiphosphate (GGDP) synthase in Escherichia coli, C30 carotenoid synthase CrtM from Staphylococcus aureus produces novel carotenoids with the asymmetrical C35 backbone.
Arnold, Frances H., Umeno, Daisuke
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Microwave-assisted Serinol Dimethoxytritylation as a Key Step in Nucleic Acid Chemistry
Cumhuriyet Science JournalNucleic acids (DNA and RNA) have widespread applications in medicinal chemistry as well as in material sciences. It is possible to increase these applications and their efficacy by introducing chemical modifications.
Zeynep Kanlidere
doaj +1 more source