Results 121 to 130 of about 36,341 (274)
Effects of baclofen on swallow motor pattern
Baclofen is a GABAB receptor agonist used clinically to manage spasticity. It has also been associated with increased duration of mechanical ventilation and rates of aspiration pneumonitis. We hypothesized that baclofen would impair pharyngeal swallow, a
Nathan W. Fielder +6 more
doaj +1 more source
Tolerance to continuous intrathecal baclofen infusion can be reversed by pulsatile bolus infusion [PDF]
Herre W. Heetla +2 more
openalex +1 more source
Pathology of PSS and the antispastic mechanism of MSSA: A focus on cerebral blood flow augmentation and 5‐HT2AR‐mediated KCC2 activation. Abbreviations: CST, corticospinal tract; CRT, corticoreticular tract, RST, reticulospinal tract; rCBF, regional cerebral blood flow; PSS, post‐stroke spasticity. ABSTRACT Background Muscle spasticity, a prevalent and
Qin‐Yong Zhang +8 more
wiley +1 more source
Effects of baclofen on insular gain anticipation in alcohol-dependent patients — a randomized, placebo-controlled, pharmaco-fMRI pilot trial [PDF]
Patricia Pelz +10 more
openalex +1 more source
ABSTRACT Mitochondrial HMG‐CoA synthase deficiency should be suspected in infants with hypoketotic hypoglycemia, metabolic acidosis, and basal ganglia lesions. A 2‐year‐old boy with a novel HMGCS2 variant presented with refractory seizures and encephalopathy, highlighting the need for rapid metabolic and genetic evaluation for timely management.
Yasmeen Alshami +7 more
wiley +1 more source
Pharmacokinetic data on high dose baclofen administration in unhealthy alcohol user in the ICU
In the intensive care unit, alcohol intake above the NIAAA recommendations regardless of the existence of an Alcohol Use Disorder (AUD), was associated with an increased risk of death and longer time on ventilator.
Mickael Vourc'h +7 more
doaj +1 more source
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Gege Li +13 more
wiley +1 more source
Image-guided intrathecal baclofen pump catheter implantation: a technical note and case series [PDF]
Shenandoah Robinson +5 more
openalex +1 more source
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao +6 more
wiley +1 more source
THE DYNAMICS OF HISTOMORPHOLOGICAL CHANGES IN ACUTE BACLOFEN POISONING [PDF]
Olga Romanova +3 more
openalex +1 more source

