Results 171 to 180 of about 1,155,621 (272)

Curli Biogenesis: Bacterial Amyloid Assembly by the Type VIII Secretion Pathway. [PDF]

EcoSal Plus, 2019
Bhoite S, van Gerven N, Chapman MR, Remaut H.   +3 more
europepmc   +1 more source

Research Trends and Mechanistic Insights Into Natural Medicines for Alzheimer's Disease: A Bibliometric Analysis and Narrative Review

Phytotherapy Research, EarlyView.
Research landscape and mechanistic insights into natural medicines for Alzheimer's disease. ABSTRACT Natural medicines have been widely investigated for Alzheimer's disease (AD), but the development of this field and the relationship between bibliometric themes and experimental evidence remain insufficiently characterized.
Maoning Wang, Xiaolian Zhang, Huaxian Yang, Jianhe Zhao, Wentao Wei, Qian Zhao, Wenjia Wang, Yunhui Hu, Jiansong Fang   +8 more
wiley   +1 more source

Bacterial amyloid curli activates the host unfolded protein response via IRE1α in the presence of HLA-B27. [PDF]

Gut Microbes
Grando K, Bessho S, Harrell K, Kyrylchuk K, Pantoja AM, Olubajo S, Albicoro FJ, Klein-Szanto A, Tükel Ç.   +8 more
europepmc   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Anti-Biofilm Activity of Graphene Quantum Dots via Self-Assembly with Bacterial Amyloid Proteins. [PDF]

ACS Nano, 2019
Wang Y, Kadiyala U, Qu Z, Elvati P, Altheim C, Kotov NA, Violi A, VanEpps JS.   +7 more
europepmc   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Association of cerebral amyloid-\u3b2 aggregation with cognitive functioning in persons without dementia

, 2018
: Importance Cerebral amyloid-\u3b2 aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the ...
Zboch, Marzena, de Oliveira, Catarina Resende, Engelborghs, Sebastiaan, Landau, Susan M., Tijms, Betty M., Fleisher, Adam S., Mintun, Mark A., Kornhuber, Johannes, Hansson, Oskar, Mok, Vincent, Gabryelewicz, Tomasz, Sabri, Osama, Kramberger, Milica G., Froelich, Lutz, Frisoni, Giovanni B., Drzezga, Alexander, Madsen, Karine, Jagust, William J., Mroczko, Barbara, Verhey, Frans R. J., Mattsson, Niklas, Sanchez-Juan, Pascual, Verbeek, Marcel M., Visser, Pieter Jelle, Parnetti, Lucilla, Fagan, Anne M., Popp, Julius, Vandenberghe, Rik, Camus, Vincent, Rowe, Christopher C., Ossenkoppele, Rik, Wolk, David A., Rinne, Juha O., Jansen, Willemijn J., Lleo, Alberto, Rabinovici, Gil D., Klunk, William E., Wallin, Anders, Brooks, David J., Ivanoiu, Adrian, Fladby, Tormod, Chetelat, Gael, Meyer, Philipp T., Na, Duk L., Villemagne, Victor L., Tsolaki, Magda, Aalten, Pauline, Kapaki, Elisabeth, Newberg, Andrew, Lee, Dong Young, Molinuevo, Jose Luis, de Mendonca, Alexandre, van der Flier, Wiesje M., Nordberg, Agneta, Sarazin, Marie, Hildebrandt, Helmut, Scheltens, Philip   +56 more
core  

Cyanogenic Compounds, Physicochemical Parameters and Metals in Water From Cassava Processing Areas: A Study in the Brazilian Amazon, Using Multivariate Analysis

Environmental Toxicology, EarlyView.
ABSTRACT This study evaluated the water quality of artesian wells and effluents generated in cassava processing in a rural area of Bragança, Pará, with emphasis on physicochemical parameters, multielement composition, and cyanogenic compounds. The well water presented specific nonconformities, highlighting pH values below the recommended level and high
Alana Coêlho Maciel, Mariane Gama Nabiça, Luciana Pinheiro Santos, Thiago de Melo e Silva, Elivaldo Nunes Modesto Junior, Heronides Adonias Dantas Filho, Charles Miller de Souza Borges, Kelly das Graças Fernandes Dantas, Simone de Fátima Pinheiro Pereira, Ivan Carlos da Costa Barbosa, Beni Jequicene Mussengue Chaúque, Rosinelson da Silva Pena, Nayara Macêdo Peixoto Araújo, Alessandra Santos Lopes   +13 more
wiley   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source