Results 221 to 230 of about 1,155,621 (272)
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
The Gut-Brain Axis in Neurodegeneration: Mechanistic Links Between Dysbiosis and Neuropathology. [PDF]
Azimzadeh M +5 more
europepmc +1 more source
Periodontitis and metabolic dysfunction‐associated steatotic liver disease
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon +6 more
wiley +1 more source
Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata +3 more
wiley +1 more source
Oral health and systemic health outcomes: A call for interdisciplinary action
Abstract Objectives To make the case, from periodontology and dental public health, for interdisciplinary action on oral and systemic health, and to set out recommendations for practice, policy, education, and research. Materials and Methods A joint working group of the European Federation of Periodontology (EFP) and the European Association of Dental ...
Moritz Kebschull +29 more
wiley +1 more source
Beyond the Microbial Hypothesis: Shared Genetic, Osteoimmune and Vascular Mechanisms in the Oral-Brain Axis Linking Periodontitis and Alzheimer's Disease. [PDF]
Kabbashi S, Ahmed M, Chetty M.
europepmc +1 more source
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira +6 more
wiley +1 more source
Perspective of retinal Chlamydia pneumoniae infection in Alzheimer's disease pathogenesis. [PDF]
Baixu H, Qing W, Chunming X.
europepmc +1 more source
Effects of a Dietary Supplementation of Bovine Colostrum in Dogs With Atopic Dermatitis
ABSTRACT Background Bovine colostrum (BC) shows immunomodulatory properties, which could be beneficial in the management of chronic immune‐mediated diseases such as canine atopic dermatitis (cAD). Objective To assess if a BC supplementation affects selected immune variables and clinical signs in cAD.
Laura Schäfer +2 more
wiley +1 more source
Translating gut microbiome research into therapies for type 1 diabetes
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok +2 more
wiley +1 more source

