Results 101 to 110 of about 6,595 (270)

An investigation to observe the effect of DMSO and glycerol on the aggregation of lysozyme [PDF]

, 2014
Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, Prions Disease are few among many diseases caused due to the aggregation of misfolded proteins, which eventually leads to the formation of amyloids.
Sahoo, A K
core  

Functional Amyloid and Other Protein Fibers in the Biofilm Matrix [PDF]

, 2018
Biofilms are ubiquitous in the natural and man-made environment. They are defined as microbes that are encapsulated in an extracellular, self-produced, biofilm matrix.
Alteri, Amdursky, Arranz, Ayakawa, Baldwin, Barnhart, Basaraba, Bayer, Besingi, Bieler, Blanco, Boles, Bowen, Branda, Branda, Bély, Cait E. MacPhee, Chai, Channon, Chapman, Chiti, Claessen, Claessen, Collinson, Costalonga, Costerton, Crick, Cucarella, De Ferrari, de Lorenzo, Diehl, Dragoš, Dueholm, Dueholm, Dueholm, Dutta, Elliot, Elliot Erskine, Erskine, Esteban, Evans, Fitzpatrick, Fitzpatrick, Flemming, Frederick, Gophna, Goyal, Greenwald, Hammer, Hirano, Hobley, Howie, Howie, Hudson, Jackson, Jain, Kahn, Kayed, Kelly, Kim, Kyle, Langkilde, Larsen, Larsen, Larson, Larson, Lei, Levine, Lopez, López-Ochoa, Makin, Mann, Markande, Mehlin, Micsonai, Moradali, Nenninger, Nicola R. Stanley-Wall, O'Nuallain, Oh, Ojha, Oli, Olsén, Otto, Otzen, Peterson, Pras, Ramsugit, Rigano, Rohde, Romero, Romero, Romero, Romero, Ryu, Römling, Saupe, Sawyer, Schmidt, Schwartz, Schwartz, Serra, Serra, Shahnawaz, Shewmaker, Sipe, Sipe, Skariyachan, Smith, Stsiapura, Stöver, Sugimoto, Taglialegna, Taglialegna, Tayeb-Fligelman, Thongsomboon, Tian, Uhlich, van der Wel, Van Gerven, Vassar, Vidakovic, Vidal, Vlamakis, Wang, Wang, Wasmer, Wildermuth, Xiao, Yang, Zeng, Zheng, Zimaro   +132 more
core   +2 more sources

Bacterial Amyloids

, 2019
Amyloids are supramolecular protein assemblies based on fibrillar arrangements of β- sheets that were first found as linked to neurodegenerative and systemic human diseases. However, there is now overwhelming evidence on alternative roles of amyloids as functional assemblies and as epigenetic determinants of beneficial traits, both in ...
Marcoleta, Andrés, Wien, Frank, Arluison, Véronique, Lagos, Rosalba, Giraldo, R.   +4 more
openaire   +1 more source

Bacterial enzymes effectively digest Alzheimer's β-amyloid peptide

Brain Research Bulletin, 2014
Aggregated β-amyloid peptides play key roles in the development of Alzheimer's disease, and recent evidence suggests that microbial particles, among others, can facilitate their polymerization. Bacterial enzymes, however, have been proved to be beneficial in degrading pathological fibrillar structures in clinical settings, such as strepto-kinases in ...
Danilova Y., Shagimardanova E., Margulis A., Toymentseva A., Balaban N., Rudakova N., Rizvanov A., Sharipova M., Palotás A.   +8 more
openaire   +4 more sources

Multivariate Analysis of Hematological Stress Biomarkers and Welfare Domains in Organic and Intensive Pig Farming in Italy: A Pilot Study

Animal Research and One Health, EarlyView.
Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito, Talal Hassan, Antonio Marco Maisano, Stefania Bergagna, Cecilia Guasco, Barbara Miniscalco, Martina Tarantola, Elena Colombino, Claudio Caruso, Ahsan Muhammad, Silvia Mioletti, Laura Tomassone, Massimiliano Tursi, Cristina Vercelli, Giovanni Loris Alborali, Maria Teresa Capucchio   +15 more
wiley   +1 more source

An enhanced recombinant amino-terminal acetylation system and novel in vivo high-throughput screen for molecules affection alpha-synuclein oligomerisation [PDF]

, 2017
Amino terminal acetylation is a ubiquitous protein modification affecting the majority of eukaryote proteins to regulate stability and function. We describe an optimised recombinant expression system for rapid production of aminoterminal-acetylated ...
Arnesen, Bartels, Ben-Bassat, Bodner, Cheruvara, Cremades, Dikiy, George, Gromyko, Gunning, Haldimann, Hebron, Hebron, Johnson, Kalvik, Kim, Kodama, Liu, Mahul-Mellier, Maltsev, Nesterov, Paleologou, Park, Perni, Rodriguez, Saunders, Schmidt, Secchi, Sommese, Starheim, Trexler, Wegerer, Yi   +32 more
core   +2 more sources

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

Defining motility in the Staphylococci [PDF]

, 2017
The ability of bacteria to move is critical for their survival in diverse environments and multiple ways have evolved to achieve this. Two forms of motility have recently been described for Staphylococcus aureus, an organism previously considered to be ...
A Borges, A Borges, A Kamp, A Martínez, A Peschel, A Rio del, AL Cogen, ATY Yeung, B Nan, BGJ Surewaard, BR Boles, C Fuqua, C Josenhans, C Kaito, C Kaito, C Kaito, C Kaito, C Wolgemuth, CP Gordon, D Debois, D Ditmarsch van, D Kaiser, D Kretschmer, D López, D Nair, D Vorkapic, DB Kearns, DJ Gonzalez, DK Jain, DR Boone, E Dordet-Frisoni, E Déziel, E Hoiczyk, E Laanto, E Tsompanidou, E Tsompanidou, E Tsompanidou, EJ Murray, EJG Pollitt, EJG Pollitt, Eric J. G. Pollitt, F Banovic, F Harrison, F Pfeifer, FD Lowy, G Browning, G Döring, GA Somerville, GH Wadhams, GYC Cheung, GYC Cheung, GYC Cheung, H Kizaki, H McCarthy, H Reichenbach, H Sun, H-S Joo, I Margarit, J Adler, J Henrichsen, J Henrichsen, J Hübscher, J Tremblay, J Tremblay, JA Geoghegan, JB Xavier, JD Shrout, JD Watrous, JE Patrick, JP O’Gara, JP Ramsay, JS Wright, K Schwartz, K Schwartz, K Schwartz, K Traber, KD Young, KF Jarrell, KH Keller, L Craig, M Burkart, M Ikuo, M Laabei, M Miyata, M Otto, M Otto, M Otto, M Rautenberg, M Schuster, M-H Lin, ME Davey, MJ McBride, MJ McBride, N Schuergers, NC Caiazza, NK Archer, P Mayville, P Williams, PD Fey, R Wheeler, RM Harshey, RP Burchard, RP Novick, S Brown, S Periasamy, SA West, SB Guttenplan, SE Darch, SJ Giovannoni, SM Szczepanek, SS Chatterjee, SS Chatterjee, SS Chatterjee, Stephen P. Diggle, SY Queck, T Mignot, T Ueda, T Ursell, TE Angelini, U Fluckiger, VG Fowler, Y Benito, Y Omae, Y Omae   +123 more
core   +3 more sources

Analysis of Single Particles of Amyloid Beta and α‐Synuclein With Seeded Amplification for the Diagnosis of Alzheimer's and Parkinson's Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala, Marlene Pils, Oliver Bannach, Gültekin Tamgüney, Detlev Riesner   +4 more
wiley   +1 more source

Cross-Species Amyloid-like Features Shared by Mammalian and Clostridioides difficile Proteins

Microorganisms
Functional amyloids are widely distributed in bacteria and play important roles in biofilm formation and microbial physiology. However, most currently known bacterial amyloids have been identified through sequence homology to a limited number of ...
Weichen Gong
doaj   +1 more source