Results 121 to 130 of about 6,595 (270)
Background & Aims: Mounting evidence suggests the gastrointestinal microbiome is a determinant of peripheral immunity and central neurodegeneration, but the local disease mechanisms remain unknown.
Peter Verstraelen +14 more
doaj +1 more source
Computational Analysis of Candidate Prion-Like Proteins in Bacteria and Their Role
Prion proteins were initially associated with diseases such as Creutzfeldt Jakob and transmissible spongiform encephalopathies. However, deeper research revealed them as versatile tools, exploited by the cells to execute fascinating functions, acting as ...
Valentin eIglesias +2 more
doaj +1 more source
Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq +2 more
wiley +1 more source
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng +5 more
wiley +1 more source
Investigation on the effect of artificial chaperones on lysozyme aggregation [PDF]
Protein misfolding and aggregation is an unwanted phenomenon occurring in cells which is one of the cause of various degenerative diseases. The conformational changes occurring due to certain environmental conditions and due to the mutations in the ...
Parihary, Avishek
core
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
lnsights into bacterial functional amyloids using the staphyiococcal Bap protein asan amyloid model
Functional arnyloids are key cornponents of the biofilrn rnatrix of many bacteria. These structures provide resistance toward proteases and harsh denaturing conditions, and strengthening against rnechanical or degradative disruption. The Biofilrn associated protein Bap of Staphylococcus aureus is a surface protein able to forrn arnyloid-like structures
openaire +3 more sources
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou +6 more
wiley +1 more source
Prion 2025, held in Armação dos Búzios, Brazil (3–7 November 2025), was the first PRION congress in Latin America and brought together 260 participants from 22 countries.
Tuane C. R. G Vieira, Jerson Lima Silva
doaj +1 more source

