Results 71 to 80 of about 286,033 (295)

Structure and function of bacterial dynamin-like proteins [PDF]

, 2012
Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
core   +1 more source

Synthetic cell division via membrane-transforming molecular assemblies

BMC Biology, 2019
Reproduction, i.e. the ability to produce new individuals from a parent organism, is a hallmark of living matter. Even the simplest forms of reproduction require cell division: attempts to create a designer cell therefore should include a synthetic cell ...
Simon Kretschmer, Kristina A. Ganzinger, Henri G. Franquelim, Petra Schwille   +3 more
doaj   +1 more source

Bacterial Growth and Cell Division: a Mycobacterial Perspective [PDF]

Microbiology and Molecular Biology Reviews, 2008
SUMMARYThe genusMycobacteriumis best known for its two major pathogenic species,M. tuberculosisandM. leprae, the causative agents of two of the world's oldest diseases, tuberculosis and leprosy, respectively.M. tuberculosiskills approximately two million people each year and is thought to latently infect one-third of the world's population.
Hett, Erik C., Rubin, Eric J.
openaire   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pbp4 is likely involved in cell division of the longitudinally dividing bacterium candidatus thiosymbion oneisti [PDF]

, 2021
Peptidoglycan (PG) is essential for bacterial survival and maintaining cell shape. The rod-shaped model bacterium Escherichia coli has a set of seven endopeptidases that remodel the PG during cell growth.
Tanneke den Blaauwen, Wang, Jinglan,, Alvarez, Laura,, Wang, Jinglan, Alvarez, Laura, Bulgheresi, Silvia,, Felipe Cava, Wang, J., Cava, Felipe,, Cava, Felipe, Laura Alvarez, Alvarez, L., den Blaauwen, T.; id_orcid, Blaauwen, Tanneke Den, Bulgheresi, S., Silvia Bulgheresi, Cava, F., Bulgheresi, Silvia, den Blaauwen, T., Jinglan Wang, Blaauwen, Tanneke Den,   +20 more
core   +1 more source

Mycobacterium Transcriptional Factor BlaI Regulates Cell Division and Growth and Potentiates β-Lactam Antibiotic Efficacy Against Mycobacteria

Microorganisms
Cell division is critical for the survival, growth, pathogenesis, and antibiotic susceptibility of Mycobacterium tuberculosis (Mtb). However, the regulatory networks governing the transcription of genes involved in cell growth and division in Mtb remain ...
Junqi Xu, Mingjun Zhang, Fuling Xie, Junfeng Zhen, Yuerigu Abuliken, Chaoyun Gao, Yongdong Dai, Zhiyong Jiang, Peibo Li, Jianping Xie   +9 more
doaj   +1 more source

Instructive simulation of the bacterial cell division cycle [PDF]

Microbiology, 2011
The coupling between chromosome replication and cell division includes temporal and spatial elements. In bacteria, these have globally been resolved during the last 40 years, but their full details and action mechanisms are still under intensive study.
Arieh, Zaritsky, Ping, Wang, Norbert O E, Vischer   +2 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The juxtamembrane domain of StkP is phosphorylated and influences cell division in Streptococcus pneumoniae

mBio
Eukaryotic-like membrane Ser/Thr protein kinases play a pivotal role in different aspects of bacterial physiology. In contrast to the diversity of their extracellular domains, their cytoplasmic catalytic domains are highly conserved.
Mélisse Hamidi, Sathya Narayanan Nagarajan, Vaishnavi Ravikumar, Virginie Gueguen-Chaignon, Cédric Laguri, Céline Freton, Ivan Mijakovic, Jean-Pierre Simorre, Stéphanie Ravaud, Christophe Grangeasse   +9 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source