Results 71 to 80 of about 7,099,213 (281)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The juxtamembrane domain of StkP is phosphorylated and influences cell division in Streptococcus pneumoniae

mBio
Eukaryotic-like membrane Ser/Thr protein kinases play a pivotal role in different aspects of bacterial physiology. In contrast to the diversity of their extracellular domains, their cytoplasmic catalytic domains are highly conserved.
Mélisse Hamidi, Sathya Narayanan Nagarajan, Vaishnavi Ravikumar, Virginie Gueguen-Chaignon, Cédric Laguri, Céline Freton, Ivan Mijakovic, Jean-Pierre Simorre, Stéphanie Ravaud, Christophe Grangeasse   +9 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Cell division in walled Bacillus subtilis and cell wall-lacking Acholeplasma laidlawii [PDF]

, 2019
Bacterial resistance to the antibiotics is an increasing worldwide health problem, and the inhibition of the bacterial divisome, especially by targeting the central cell division mediator FtsZ, has been regarded as a promising strategy for antibiotic ...
Gao, Y.
core   +10 more sources

The actin homologue MreB organizes the bacterial cell membrane [PDF]

, 2014
The eukaryotic cortical actin cytoskeleton creates specific lipid domains, including lipid rafts, which determine the distribution of many membrane proteins. Here we show that the bacterial actin homologue MreB displays a comparable activity.
Burmann, F., Strahl, H., Hamoen, L.W., Hamoen, L., Hamoen, L.W.; id_orcid   +4 more
core   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The minimalistic divisome reveals power of the cell division machinery [PDF]

, 2019
Bacterial resistance towards antibiotics is an increasing worldwide health problem with the potential to seriously endanger modern medicine without prudent measures.
Saaki, T.N.V.
core   +9 more sources

Distinct modes of cell division drive Anaplasma phagocytophilum morphotype development and the infection cycle

mBio
Pleomorphism is an evolutionary adaptation by which diverse microorganisms maximize their fitness by transitioning between morphologically distinct forms that perform disparate functions in response to the local microenvironment.
Travis J. Chiarelli, Savannah E. Sanchez, Mary Clark H. Lind, Nathaniel S. O'Bier, Curtis B. Read, Richard T. Marconi, Jason A. Carlyon   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colocalization and interaction between elongasome and divisome during a preparative cell division phase in Escherichia coli

, 2013
The rod-shaped bacterium Escherichia coli grows by insertion of peptidoglycan into the lateral wall during cell elongation and synthesis of new poles during cell division.
Verheul, Jolanda, Hoogendoorn, Eelco, Alexeeva, Svetlana, Vollmer, Waldemar, Banzhaf, Manuel; id_orcid, van der Ploeg, René, Vollmer, W., Vischer, Norbert O E, Postma, Marten, Verheul, J., Postma, M., Alexeeva, S., Verheul, J.; id_orcid, Alexeeva, S.V., van der Ploeg, R., den Blaauwen, T.; id_orcid, Banzhaf, M., Vischer, N.O.E., den Blaauwen, T., Blaauwen, T., den, Hoogendoorn, E., Ploeg, R., van der, den Blaauwen, Tanneke   +22 more
core   +1 more source