Results 81 to 90 of about 7,099,213 (281)

The conserved DNA-binding protein WhiA is involved in cell division in Bacillus subtilis [PDF]

, 2013
Bacterial cell division is a highly coordinated process that begins with the polymerization of the tubulin-like protein FtsZ at midcell. FtsZ polymerization is regulated by a set of conserved cell division proteins, including ZapA.
Siersma, T., Claessen, D., Surdova, K., Jonker, M.J., Errington, J., Gamba, P., Hamoen, L.W., Hamoen, L.W.; id_orcid   +7 more
core   +3 more sources

Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations

Frontiers in Microbiology, 2018
Model bacteria, such as E. coli and B. subtilis, tightly regulate cell cycle progression to achieve consistent cell size distributions and replication dynamics. Many of the hallmark features of these model bacteria, including lateral cell wall elongation
Michelle M. Logsdon, Michelle M. Logsdon, Bree B. Aldridge, Bree B. Aldridge, Bree B. Aldridge   +4 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Caloric restriction causes symmetric cell division and delays aging in Escherichia coli [PDF]

, 2008
Aging is one of the most intriguing processes of biology and despite decades of research, many aspects of aging are poorly understood. Aging is known to occur in bacteria and yeast that divide with morphological asymmetry.
Milind G. Watve, Snehal Bari, Uttara Lele, Samit Watve, Prajakta Belsare, Sarika Karande   +5 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Prokaryotic cell division: flexible and diverse

, 2013
Gram-negative rod-shaped bacteria have different approaches to position the cell division initiating Z-ring at the correct moment in their cell division cycle.
den Blaauwen, T.; id_orcid, den Blaauwen, T.   +1 more
core   +1 more source

MioC and GidA proteins promote cell division in E. coli

Frontiers in Microbiology, 2015
The well-conserved genes surrounding the E. coli replication origin, mioC and gidA, do not affect chromosome replication and have little known function.
Mark eLies, Bryan J. Visser, Mohan C. Joshi, David eMagnan, David eBates, David eBates   +5 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Size-independent symmetric division in extraordinarily long cells [PDF]

, 2014
Two long-standing paradigms in biology are that cells belonging to the same population exhibit little deviation from their average size and that symmetric cell division is size limited.
Heindl, N.R., Pende, N., Ott, J., den Blaauwen, T.; id_orcid, Bulgheresi, S., Heindl, N., Gruber-Vodicka, H.R., den Blaauwen, T., Gruber-Vodicka, H., Leisch, N.   +9 more
core   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source