Results 181 to 190 of about 1,943,316 (288)

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Neisseria meningitidis, 2004 [PDF]

ABCs Areas: California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut; Georgia; Maryland; Minnesota; New Mexico; New York (15 county Rochester and Albany areas); Oregon; Tennessee (11 urban counties)ABCs Population: The ...

core  

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Spatial proximity dictates bacterial competition and expansion in microbial communities. [PDF]

Nat Commun
Şimşek E, Villalobos CA, Sahu K, Zhou Z, Luo N, Lee D, Ma HR, Anderson DJ, Lee CT, You L.   +9 more
europepmc   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Haemophilus influenzae, 1998 [PDF]

ABCs Areas: California (3 county San Francisco Bay area); Connecticut; Georgia (20 county Atlanta area); Maryland; Minnesota; New York (7 county Rochester area); Oregon; Tennessee (5 urban counties)ABCs Population: The surveillance areas represent 26,514,

core  

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Haemophilus influenzae, 1999 [PDF]

ABCs Areas: California (3 county San Francisco Bay area); Connecticut; Georgia (20 county Atlanta area); Maryland; Minnesota; New York (15 county Rochester/Albany area); Oregon; Tennessee (5 urban countiesABCs Population: The surveillance areas represent

core  

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

A Pseudomonas aeruginosa endolytic muramidase targets cell-wall peptidoglycan in bacterial competition. [PDF]

J Biol Chem
Wang T, Zhang L, Lee M, Yan W, Liu Q, Wang C, Feltzer R, Hesek D, Mobashery S, Zhang L, Liang H.   +10 more
europepmc   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Neisseria meningitidis, 2001 [PDF]

ABCs Areas: California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut; Georgia; Maryland; Minnesota; New York (15 county Rochester/Albany area); Oregon; Tennessee (11 county area).ABCs Population: The surveillance areas ...

core