Dual RNA-seq reveals a type 6 secretion system-dependent blockage of TNF-α signaling and BicA as a Burkholderia pseudomallei virulence factor important during gastrointestinal infection [PDF]
Gut Microbes, 2022 Melioidosis is a disease caused by the Gram-negative bacillus Burkholderia pseudomallei (Bpm), commonly found in soil and water of endemic areas. Naturally acquired human melioidosis infections can result from either exposure through percutaneous ...
Javier I. Sanchez-Villamil +4 more
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Characterizing the Type 6 Secretion System (T6SS) and its role in the virulence of avian pathogenic Escherichia coli strain APECO18 [PDF]
PeerJ, 2021 Avian pathogenic E. coli is the causative agent of extra-intestinal infections in birds known as colibacillosis, which can manifest as localized or systemic infections.
Aline L. de Oliveira +5 more
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Vibrio vulnificus Type 6 Secretion System 1 Contains Anti-Bacterial Properties. [PDF]
PLoS ONE, 2016 Vibrio vulnificus is a bacterium responsible for severe gastroenteritis, sepsis and wound infections. Gastroenteritis and sepsis are commonly associated with the consumption of raw oysters, whereas wound infection is often associated with the handling of
Selina R Church +4 more
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Type 1 fimbriae-mediated collective protection against type 6 secretion system attacks [PDF]
mBioBacterial competition may rely on secretion systems such as the type 6 secretion system (T6SS), which punctures and releases toxic molecules into neighboring cells.
Margot Marie Dessartine +4 more
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Neisseria subflava Type 6 Secretion System competition with bacterial and fungal species [PDF]
Applied Microbiology and BiotechnologyThe aim of this study was to assess whether a Type VI Secretion System (T6SS) present in the commensal, non-pathogenic Neisseria subflava strain KU1003-01 plays a role in competition between these bacteria and other commensal and pathogenic Gram-negative
Alan Calder, Lori A. S. Snyder
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Yersinia pestis BipA is a novel regulator of pesticin and a type 6 secretion system [PDF]
Infection and ImmunityYersinia pestis is a gram-negative bacterium and the causative agent of bubonic, septicemic, and pneumonic plague. Y. pestis is most commonly transmitted to humans by infected fleas that deposit the bacteria into the dermis at the bite site, leading to ...
Madeleine G. Scott +4 more
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A type 6 secretion system (T6SS) encoded gene within Salmonella enterica serovar Enteritidis contributes to virulence [PDF]
Virulence, 2018 Bacteria interact with their host through protein secretion systems and surface structures. Pathogenic bacteria encode protein secretion systems that promote the invasion of the host's tissue, the evasion of the host's immune response, the thwarting ...
Bryan Troxell
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Role of the type 6 secretion system on apoptosis and macrophage polarization during Burkholderia pseudomallei infection. [PDF]
PLoS Neglected Tropical DiseasesBurkholderia pseudomallei (Bpm) is the causative agent of the disease melioidosis. As a facultative intracellular pathogen, Bpm has a complex lifestyle that culminates in cell-to-cell fusion and multinucleated giant cells (MNGCs) formation. The virulence
Jacob L Stockton +2 more
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Identification of Virulence Genes Associated with Pathogenicity of Translocating Escherichia coli with Special Reference to the Type 6 Secretion System [PDF]
MicroorganismsRecent genomic characterisation of translocating Escherichia coli HMLN-1 isolated from mesenteric lymph nodes (MLNs) and blood of a patient with a fatal case of pancreatitis revealed the presence of a type 6 secretion system (T6SS) that was not present ...
Behnoush Asgari +6 more
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mSphere, 2023 Burkholderia pseudomallei (Bpm) is the causative agent of melioidosis disease. Bpm is a facultative intracellular pathogen with a complex life cycle inside host cells.
Jacob L. Stockton +3 more
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