Distribution and diversity of bacterial secretion systems across metagenomic datasets [PDF]
, 2012 Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from ...
Egan, Frank +3 more
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Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]
, 2014 The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James +16 more
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CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL. [PDF]
, 2012 Helicobacter pylori, the causative agent of type B gastritis, peptic ulcers, gastric adenocarcinoma and MALT lymphoma, uses the Cag type IV secretion system to induce a strong proinflammatory response in the gastric mucosa and to inject its effector ...
Haas, Rainer +17 more
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Type VI secretion: a beginner's guide [PDF]
, 2008 Type VI secretion is a newly described mechanism for protein transport across the cell envelope of Gram-negative bacteria. Components that have been partially characterised include an IcmF homologue, the ATPase ClpV, a regulatory FHA domain protein and ...
Bailey, Christopher +7 more
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Analysis of the expression, secretion and translocation of the Salmonella enterica type III secretion system effector SteA. [PDF]
PLoS ONE, 2011 Many Gram-negative pathogens possess virulence-related type III secretion systems. Salmonella enterica uses two of these systems, encoded on the pathogenicity islands SPI-1 and SPI-2, respectively, to translocate more than 30 effector proteins into ...
Elena Cardenal-Muñoz +1 more
doaj +1 more source
Francisella novicida pathogenicity island encoded proteins were secreted during infection of macrophage-like cells. [PDF]
PLoS ONE, 2014 Intracellular pathogens and other organisms have evolved mechanisms to exploit host cells for their life cycles. Virulence genes of some intracellular bacteria responsible for these mechanisms are located in pathogenicity islands, such as secretion ...
Rebekah F Hare, Karsten Hueffer
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Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system [PDF]
, 2011 The intestinal immune system and the epithelium are the first line of defense in the gut. Constantly exposed to microorganisms from the environment, the gut has complex defense mechanisms to prevent infections, as well as regulatory pathways to tolerate ...
Anna Vossenkämper +5 more
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Evaluation of the roles played by Hcp and VgrG type 6 secretion system effectors in Aeromonas hydrophila SSU pathogenesis [PDF]
Microbiology, 2013 Aeromonas hydrophila, a Gram-negative bacterium, is an emerging human pathogen equipped with both a type 3 and a type 6 secretion system (T6SS). In this study, we evaluated the roles played by paralogous T6SS effector proteins, hemolysin co-regulated proteins (Hcp-1 and -2) and valine glycine repeat G (VgrG-1, -2 and -3) protein family members in A ...
Jian, Sha +7 more
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Proteomic Analysis of the GacA Response Regulator in Pseudomonas chlororaphis O6
Research in Plant Disease, 2018 The GacS/GacA system in the root colonizer Pseudomonas chlororaphis O6 is a key regulatory system of many traits relevant to the plant probiotic nature of this bacterium.
Anne J. Anderson, Young Cheol Kim
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Type VI secretion system : secretion by a contractile nanomachine [PDF]
, 2015 The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative bacteria. Several key components of T6SS are evolutionarily related to components of contractile nanomachines such as phages and R-type pyocins. The T6SS assembly is
Basler, Marek, Basler M
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