L-type (Loaf) Cervical Secretion Crystallization Directionality Biomarker Study [PDF]
Background: Cervical discharge is considered a hydrogel, which is part liquid and part solid. Under physiological conditions, the characteristic “fern-leaf” arborization is proportional to the circulating estradiol concentration and maximal in the ...
José María Murcia Lora +6 more
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Secretin interactions in the type II secretion system [PDF]
PhDThe type II secretion system (T2SS) is the major terminal branch of the general secretory pathway. It is composed of 12-15 proteins, most in multiple copies, and spans the inner and outer membranes of Gram-negative bacteria.
Gu, Shuang
core +4 more sources
Vibrio parahaemolyticus is a bacterial pathogen that becomes lethal to Penaeus shrimps when acquiring the pVA1-type plasmid carrying the PirABvp genes, causing acute hepatopancreatic necrosis disease (AHPND). This disease causes significant losses across
Alejandro Castellanos +5 more
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Exploration of chlamydial type III secretion system reconstitution in Escherichia coli. [PDF]
BACKGROUND:Type III secretion system is a virulent factor for many pathogens, and is thought to play multiple roles in the development cycle and pathogenesis of chlamydia, an important human pathogen.
Xiaofeng Bao +2 more
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Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution
Electron cryo-microscopy (cryo-EM) has emerged as a powerful method by which to obtain three-dimensional (3D) structures of macromolecular complexes at atomic or near-atomic resolution.
Guillaume Bouvier +4 more
doaj +1 more source
High levels of DegU-P activate an Esat-6-like secretion system in Bacillus subtilis. [PDF]
The recently discovered Type VII/Esat-6 secretion systems seem to be widespread among bacteria of the phyla Actinobacteria and Firmicutes. In some species they play an important role in pathogenic interactions with eukaryotic hosts.
Catarina Baptista +2 more
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Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]
The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James +16 more
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Effective identification of bacterial type III secretion signals using joint element features. [PDF]
Type III secretion system (T3SS) plays important roles in bacteria and host cell interactions by specifically translocating type III effectors into the cytoplasm of the host cells.
Yejun Wang +4 more
doaj +1 more source
CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL. [PDF]
Helicobacter pylori, the causative agent of type B gastritis, peptic ulcers, gastric adenocarcinoma and MALT lymphoma, uses the Cag type IV secretion system to induce a strong proinflammatory response in the gastric mucosa and to inject its effector ...
Haas, Rainer +17 more
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Shiga-toxin-producing Escherichia coli (STEC) has become an important pathogen that can cause diarrhea, hemorrhagic colitis and hemolytic uremic syndrome (HUS) in humans.
Jaime Vazquez-Lopez +1 more
doaj +1 more source

