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Type 1 fimbriae-mediated collective protection against type 6 secretion system attacks [PDF]

open access: yesmBio
Bacterial competition may rely on secretion systems such as the type 6 secretion system (T6SS), which punctures and releases toxic molecules into neighboring cells.
Margot Marie Dessartine   +4 more
doaj   +5 more sources

Neisseria subflava Type 6 Secretion System competition with bacterial and fungal species [PDF]

open access: yesApplied Microbiology and Biotechnology
The aim of this study was to assess whether a Type VI Secretion System (T6SS) present in the commensal, non-pathogenic Neisseria subflava strain KU1003-01 plays a role in competition between these bacteria and other commensal and pathogenic Gram-negative
Alan Calder, Lori A. S. Snyder
doaj   +5 more sources

Yersinia pestis BipA is a novel regulator of pesticin and a type 6 secretion system [PDF]

open access: yesInfection and Immunity
Yersinia pestis is a gram-negative bacterium and the causative agent of bubonic, septicemic, and pneumonic plague. Y. pestis is most commonly transmitted to humans by infected fleas that deposit the bacteria into the dermis at the bite site, leading to ...
Madeleine G. Scott   +4 more
doaj   +5 more sources

Role of the type 6 secretion system on apoptosis and macrophage polarization during Burkholderia pseudomallei infection. [PDF]

open access: yesPLoS Neglected Tropical Diseases
Burkholderia pseudomallei (Bpm) is the causative agent of the disease melioidosis. As a facultative intracellular pathogen, Bpm has a complex lifestyle that culminates in cell-to-cell fusion and multinucleated giant cells (MNGCs) formation. The virulence
Jacob L Stockton   +2 more
doaj   +4 more sources

A type 6 secretion system (T6SS) encoded gene within Salmonella enterica serovar Enteritidis contributes to virulence [PDF]

open access: yesVirulence, 2018
Bacteria interact with their host through protein secretion systems and surface structures. Pathogenic bacteria encode protein secretion systems that promote the invasion of the host's tissue, the evasion of the host's immune response, the thwarting ...
Bryan Troxell
doaj   +4 more sources

Identification of Virulence Genes Associated with Pathogenicity of Translocating Escherichia coli with Special Reference to the Type 6 Secretion System [PDF]

open access: yesMicroorganisms
Recent genomic characterisation of translocating Escherichia coli HMLN-1 isolated from mesenteric lymph nodes (MLNs) and blood of a patient with a fatal case of pancreatitis revealed the presence of a type 6 secretion system (T6SS) that was not present ...
Behnoush Asgari   +6 more
doaj   +5 more sources

Multiplicity of type 6 secretion system toxins limits the evolution of resistance [PDF]

open access: yesProceedings of the National Academy of Sciences
The bacterial type 6 secretion system (T6SS) is a toxin-injecting nanoweapon that mediates competition in plant- and animal-associated microbial communities. Bacteria can evolve de novo resistance against T6SS attacks, but resistance is far from universal in natural communities, suggesting key features of T6SS weaponry may act to ...
William P. J. Smith   +5 more
openaire   +6 more sources

Type 6 Secretion System–Mediated Immunity to Type 4 Secretion System–Mediated Gene Transfer [PDF]

open access: yesScience, 2013
Bacterial Détente? Type VI secretion systems (T6SS) correspond to dynamic intracellular organelles that are functionally analogous to contractile bacteriophage tails. The T6SS of several bacteria species have been found to be responsible for antagonistic behavior that likely reflects the translocation of toxic ...
Ho, Brian T.   +2 more
openaire   +4 more sources

From Wall to Wall: How the Type 6 Secretion System Knows To Stop Growing [PDF]

open access: yesJournal of Bacteriology, 2019
There is an inseverable link between the size of a cell and the size of its subcellular components. The type 6 secretion system (T6SS) is no exception. In this issue, Stietz et al. report their analysis of the T6SS under conditions in which the cell size was altered to an extreme degree (M. S. Stietz, X. Liang, M. Wong, S. Hersch, and T. G.
Ho BT.
openaire   +4 more sources

Xenorhabdus bovienii strain jolietti uses a type 6 secretion system to kill closely related Xenorhabdus strains [PDF]

open access: yesFEMS Microbiology Ecology, 2020
ABSTRACTXenorhabdus bovienii strain jolietti (XBJ) is a Gram-negative bacterium that interacts with several organisms as a part of its life cycle. It is a beneficial symbiont of nematodes, a potent pathogen of a wide range of soil-dwelling insects and also has the ability to kill soil- and insect-associated microbes.
Rebecca M, Kochanowsky   +3 more
openaire   +3 more sources

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