Frontiers in Microbiology, 2019 The role of the Type VI secretion system (T6SS) in Campylobacter jejuni is poorly understood despite an increasing prevalence of the T6SS in recent C. jejuni isolates in humans and chickens.
Janie Liaw +14 more
doaj +1 more source
Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes
mBio, 2022 Gliding motility using cell surface adhesins, and export of proteins by the type IX secretion system (T9SS) are two phylum-specific features of the Bacteroidetes.
Rory Hennell James +4 more
doaj +1 more source
Computational analysis of the ESX-1 region of Mycobacterium tuberculosis: insights into the mechanism of type VII secretion system. [PDF]
PLoS ONE, 2011 Type VII secretion system (T7SS) is a recent discovery in bacterial secretion systems. First identified in Mycobacterium tuberculosis, this secretion system has later been reported in organisms belonging to the Actinomycetales order and even to distant ...
Chandrani Das +2 more
doaj +1 more source
Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner. [PDF]
, 2009 Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector protein via the cag-Type IV Secretion System (T4SS) into host cells is a major risk factor for severe gastric diseases, including gastric cancer.
Haas, Rainer +42 more
core +2 more sources
Accelerated Type III Secretion System 2-Dependent Enteropathogenesis by a Salmonella enterica Serovar Enteritidis PT4/6 Strain [PDF]
Infection and Immunity, 2009 ABSTRACT Salmonella enterica subsp. I serovars Typhimurium and Enteritidis are major causes of enteric disease. The pathomechanism of enteric infection by serovar Typhimurium has been studied in detail. Serovar Typhimurium employs two pathways in parallel for triggering disease, i.e., the “classical” pathway ...
Suar, M +8 more
openaire +4 more sources
Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum [PDF]
, 2006 In many plant and animal bacterial pathogens, the Type III secretion system (TTSS) that directly translocates effector proteins into the eukaryotic host cells is essential for the development of disease.
Christian Boucher +8 more
core +2 more sources
Vibrio cholerae as a predator: lessons from evolutionary principles
Frontiers in Microbiology, 2013 Diarrheal diseases are the second-most common cause of death among children under the age of five worldwide. Cholera alone, caused by the marine bacterium Vibrio cholerae, is responsible for several million cases and over 120,000 deaths annually.
Stefan ePukatzki, Daniele eProvenzano
doaj +1 more source
BMC Microbiology, 2021 Pectobacterium carotovorum subsp. carotovorum (Pcc) causes soft-rot disease in a wide variety of plants resulting in economic losses worldwide. It produces various types of bacteriocin to compete against related plant pathogens.
Huang-Pin Wu +7 more
doaj +1 more source
Burkholderia cenocepacia type VI secretion system mediates escape of type II secreted proteins into the cytoplasm of infected macrophages. [PDF]
PLoS ONE, 2012 Burkholderia cenocepacia is an opportunistic pathogen that survives intracellularly in macrophages and causes serious respiratory infections in patients with cystic fibrosis.
Roberto Rosales-Reyes +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source