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ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang +4 more
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A nanoscale visual exploration of the pathogenic effects of bacterial extracellular vesicles on host cells. [PDF]
Kang M +12 more
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The Role of Bacterial Extracellular Vesicles in the Immune Response to Pathogens, and Therapeutic Opportunities. [PDF]
Peregrino ES +6 more
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Characterisation of LPS+ bacterial extracellular vesicles along the gut-hepatic portal vein-liver axis. [PDF]
Jain H +10 more
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Role of Bacterial Extracellular Vesicles in Manipulating Infection
Infection and Immunity, 2023Mammalian-cell-derived extracellular vesicles, such as exosomes, have been a key focal point for investigating host-pathogen interactions and are major facilitators in modulating both bacterial and viral infection. However, in recent years, increasing attention has been given to extracellular vesicles produced by bacteria and the role they play in ...
Guanqi Zhao, Melissa K. Jones
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Bacterial extracellular vesicles: Emerging nanoplatforms for biomedical applications
Microbial Pathogenesis, 2023Bacterial extracellular vesicles (BEVs) are nanosized lipid bilayers generated from membranes that are filled with components derived from bacteria. BEVs are important for the physiology, pathogenicity, and interactions between bacteria and their hosts as well. BEVs represent an important mechanism of transport and interaction between cells.
Sangiliyandi Gurunathan, Jin-Hoi Kim
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Bacterial Vesicles Mediate Extracellular Electron Transfer
Environmental Science & Technology Letters, 2019Many Gram-negative bacteria are known to release outer membrane vesicles (OMVs) into the surrounding environment during normal growth; OMVs perform diverse biological and environmental functions (e...
Xing Liu +5 more
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Stochastic effects in bacterial communication mediated by extracellular vesicles
Physical Review E, 2023Quorum sensing (QS) allows bacterial cells to sense changes in local cell density and, hence, to regulate multicellular processes, including biofilm formation, regulation of virulence, and horizontal gene transfer. While, traditionally, QS was thought to involve the exchange of extracellular signal molecules free in solution, recent experiments have ...
Brian P. Weaver +2 more
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Engineered bacterial extracellular vesicles for central nervous system diseases
Journal of Controlled Release, 2023The prevalence of central nervous system (CNS) diseases is on the rise as the population ages. The presence of various obstacles, particularly the blood-brain barrier (BBB), poses a challenge for drug delivery to the CNS. An expanding body of study suggests that gut microbiota (GM) plays an important role in CNS diseases.
Ning, Ji +5 more
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