Results 61 to 70 of about 55,076 (228)

Pneumococcal extracellular vesicles mediate horizontal gene transfer via the transformation machinery

mSphere
Bacterial cells secrete extracellular vesicles (EVs), the function of which is a matter of intense investigation. Here, we show that the EVs secreted by the human pathogen Streptococcus pneumoniae (pneumococcus) are associated with bacterial DNA on their
Sarah Werner Lass, Bailey E. Smith, Shaw Camphire, Rory A. Eutsey, Jojo A. Prentice, Saigopalakrishna S. Yerneni, Ashni Arun, Andrew A. Bridges, Jason W. Rosch, James F. Conway, Phil Campbell, N. Luisa Hiller   +11 more
doaj   +1 more source

Biomimetic electrodynamic nanoparticles comprising ginger-derived extracellular vesicles for synergistic anti-infective therapy

Nature Communications, 2022
Antibacterial materials often suffer from issues around safety and application in complex in vivo environments. Here the authors report on the conjugation of electro-driven catalytic Pd-Pt nanosheets on ginger-derived extracellular vesicles for bacterial
Zhuangzhuang Qiao, Kai Zhang, Jin Liu, Daojian Cheng, Bingran Yu, Nana Zhao, Fu-Jian Xu   +6 more
doaj   +1 more source

Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine. [PDF]

J Nanobiotechnology
Extracellular vesicles (EVs) are membrane-bound vesicles that are shed or secreted from the cell membrane and enveloped by a lipid bilayer. They possess stability, low immunogenicity, and non-cytotoxicity, exhibiting extensive prospects in regenerative medicine (RM).
Guo J, Huang Z, Wang Q, Wang M, Ming Y, Chen W, Huang Y, Tang Z, Huang M, Liu H, Jia B.   +10 more
europepmc   +4 more sources

Bacterial extracellular vesicles as cell-cell communication mediators

Postępy Higieny i Medycyny Doświadczalnej, 2020
Extracellular vesicles constitute a heterogeneous group of nanoparticles, released by both prokaryotic and eukaryotic cells, which perform various biological functions and participate in cell-cell communication. Bacterial extracellular vesicles are made of lipids, proteins and nucleic acids.
Anna Chudzik, Mariola Paściak
openaire   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Extracellular vesicles enhance the efficacy of ceftiofur against intracellular bacterial infections

Synthetic and Systems Biotechnology
Bacterial infections pose a major threat to human health and economic stability. In particular, intracellular bacterial infections present significant clinical challenges due to antibiotic resistance and poor drug penetration.
Pingping Yuan, Shijie Zhou, Qianqian Li, Lin Li, Shaoqi Qu   +4 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Toward a better understanding of the ecological roles of extracellular vesicles from plant-associated bacteria

Applied and Environmental Microbiology
Extracellular vesicles (EVs) from phytobacteria are emerging key ecological actors of plant–bacteria interactions. They can promote colonization of the host by delivering virulence factors and cell wall-degrading enzymes.
Timothée Zannis-Peyrot, Fanny Nazaret, Céline Lavire, Ludovic Vial   +3 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source