Results 61 to 70 of about 358,692 (311)

The Landscape of Pseudomonas aeruginosa Membrane-Associated Proteins

Cells, 2020
Background: Pseudomonas aeruginosa cell envelope-associated proteins play a relevant role in infection mechanisms. They can contribute to the antibiotic resistance of the bacterial cells and be involved in the interaction with host cells.
Sara Motta, Davide Vecchietti, Alessandra M. Martorana, Pietro Brunetti, Giovanni Bertoni, Alessandra Polissi, Pierluigi Mauri, Dario Di Silvestre   +7 more
doaj   +1 more source

Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry

eLife, 2016
In Gram-negative bacteria, lipid asymmetry is critical for the function of the outer membrane (OM) as a selective permeability barrier, but how it is established and maintained is poorly understood.
Shuhua Thong, Bilge Ercan, F. Torta, Zhen Yang Fong, H. Y. A. Wong, M. Wenk, Shu-Sin Chng   +6 more
semanticscholar   +1 more source

Assembly of β-barrel proteins into bacterial outer membranes

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014
Membrane proteins with a β-barrel topology are found in the outer membranes of Gram-negative bacteria and in the plastids and mitochondria of eukaryotic cells. The assembly of these membrane proteins depends on a protein folding reaction (to create the barrel) and an insertion reaction (to integrate the barrel within the outer membrane).
Selkrig, Joel, Leyton, Denisse, Webb, Chaille T, Lithgow, Trevor   +3 more
openaire   +3 more sources

Mitochondrial protein import [PDF]

, 1994
The transport of nuclear-encoded proteins from the cytosol into mitochondria is mediated by targeting (signal) sequences present on precursor forms.
Neupert, Walter, Schwarz, Elisabeth
core   +1 more source

The Effect of Lipopolysaccharide Core Oligosaccharide Size on the Electrostatic Binding of Antimicrobial Proteins to Models of the Gram Negative Bacterial Outer Membrane

Langmuir, 2016
Understanding the electrostatic interactions between bacterial membranes and exogenous proteins is crucial to designing effective antimicrobial agents against Gram-negative bacteria.
Luke A. Clifton, F. Ciesielski, M. Skoda, Nicoló Paracini, S. Holt, J. Lakey   +5 more
semanticscholar   +1 more source

Outer membrane vesicles: A bacterial-derived vaccination system

Frontiers in Microbiology, 2022
Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
L. Lieberman
semanticscholar   +1 more source

Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC. [PDF]

, 2018
Fusobacterium nucleatum is a key member of the human oral biofilm. It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a ...
Abu Amar Mohamed Al Mamun, Asis Das, Bo Hu, Chenggang Wu, Hui Wu, Hung Ton-That, Jianhua Gu, Ju Huck Lee, Marvin Whiteley, Melissa D’Amore, Truc Thanh Luong   +10 more
core   +2 more sources

Mucin adsorbed by E. coli can affect neutrophil activation in vitro

FEBS Open Bio, 2020
Bacteria colonizing human intestine adhere to the gut mucosa and avoid the innate immune system. We previously demonstrated that Escherichia coli isolates can adsorb mucin from a diluted solution in vitro.
Elena Mikhalchik, Nadezhda Balabushevich, Tatiana Vakhrusheva, Alexey Sokolov, Julia Baykova, Daria Rakitina, Petr Scherbakov, Sergey Gusev, Alexander Gusev, Zaira Kharaeva, Olga Bukato, Olga Pobeguts   +11 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Polymyxins slow down lateral diffusion of proteins and lipopolysaccharide in the E. coli outer membrane

Communications Biology
Polymyxins are often administered as last resort antibiotics for Gram-negative bacterial infections. However, given unwanted side-effects, efficacy and recent reports of resistance against polymyxins, there is an urgency to develop alternatives.
Dheeraj Prakaash, Syma Khalid
doaj   +1 more source