Results 91 to 100 of about 1,657,824 (211)

The social evolution of bacterial pathogenesis [PDF]

Proceedings of the Royal Society of London. Series B: Biological Sciences, 2001
Many of the genes responsible for the virulence of bacterial pathogens are carried by mobile genetic elements that can be transferred horizontally between different bacterial lineages. Horizontal transfer of virulence-factor genes has played a profound role in the evolution of bacterial pathogens, but it is poorly understood why these genes are so ...
openaire   +2 more sources

Deciphering novel enzymatic and non-enzymatic lysine lactylation in Salmonella

Emerging Microbes and Infections
Lysine lactylation, a novel post-translational modification, is involved in multiple cellular processes. The role of lactylation remains largely unknown, especially in bacteria.
Chuanzhen Zhang, Tao Zhou, Chengxi Li, Danni Wang, Jing Tao, Xiaocen Zhu, Jie Lu, Jinjing Ni, Yu-Feng Yao   +8 more
doaj   +1 more source

A Chimeric Peptide Derived from a Bacterial Effector Protein Attenuates TLR-2/4-Mediated Production of Pro-Inflammatory Cytokines and Enhances the Cellular Availability of Gentamicin

Journal of Inflammation Research
Binita Roy Nandi,1,2 Biswaranjan Patra,1,2 Girish K Radhakrishnan1 1Laboratory of Bacterial Pathogenesis, National Institute of Animal Biotechnology, Hyderabad, Telangana, 500032, India; 2Regional Centre for Biotechnology (RCB), Faridabad, 121001 ...
Nandi BR, Patra B, Radhakrishnan GK
doaj  

Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection [PDF]

Summary: T helper (Th)17 cells mediate both protective anti-bacterial immune responses and autoimmune pathogenesis, but the distinct pathways regulating these Th17 responses remain unclear.
Wencan Zhang, Yun Shi, Zhong, Xiancai, Xiancai Zhong, Hai-hui Xue, Sun, Zuoming, Zuoming Sun, Shi, Yun, Gwack, Yousang, Wu, Hongmin, Yousang Gwack, Hongmin Wu, Zhang, Wencan, Xue, Hai-hui   +13 more
core   +1 more source

Contribution of genomics to bacterial pathogenesis

Current Opinion in Genetics & Development, 1999
Genomics is changing the landscape of modern biology. The impact is far-reaching because it provides both the most economical means of acquiring large amounts of information and because it has forced the creation of new technologies to exploit this information.
Field, D, Hood, D, Moxon, R
openaire   +3 more sources

Host Antimicrobial Peptides in Bacterial Homeostasis and Pathogenesis of Disease

, 2014
Innate immune responses function as a first line of host defense against the development of bacterial infection, and in some cases to preserve the sterility of privileged sites in the human host.
Derek Heimlich, Kevin M. Mason, Derek R. Heimlich, Kevin Mason, Alistair Harrison   +4 more
core   +1 more source

Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system

eLife, 2014
Bacteria have to avoid recognition by the host immune system in order to establish a successful infection. Peptidoglycan, the principal constituent of virtually all bacterial surfaces, is a specific molecular signature recognized by dedicated host ...
Magda Luciana Atilano, Pedro Matos Pereira, Filipa Vaz, Maria João Catalão, Patricia Reed, Inês Ramos Grilo, Rita Gonçalves Sobral, Petros Ligoxygakis, Mariana Gomes Pinho, Sérgio Raposo Filipe   +9 more
doaj   +1 more source

Orf protein modulates phage and bacterial pathways of genetic recombination [PDF]

, 2008
The emergence of novel pathogenic organisms due to the acquisition of virulencedeterminants from bacteriophages has generated significant interest in the pathways responsible for genomic rearrangements.
Bowers, Laura Yvonne
core  

A REVIEW ON EPIGENETIC REGULATION IN BACTERIAL PATHOGENESIS AND RESISTANCE [PDF]

The study of bacterial Bacterial epigenetics has become important ,because it help to understanding the mechanisms used by bacteria to regulate gene expression with keeping their DNA sequence.
Abdzaid, Ahmed Majeed, Jabbar, Ali Sabri
core   +2 more sources

NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteria

mBio
The NLRP11 protein is only expressed in primates and participates in the activation of the canonical NLRP3 and non-canonical NLRP3 inflammasome activation after infection with gram-negative bacteria. Here, we generated a series of defined NLRP11 deletion
Mateusz Szczerba, Akshaya Ganesh, María Luisa Gil-Marqués, Volker Briken, Marcia B. Goldberg   +4 more
doaj   +1 more source