Results 101 to 110 of about 1,657,824 (211)

Genomic Analysis of the Emergence of Vancomycin-Resistant Staphylococcus aureus

mBio, 2012
Staphylococcus aureus is a human commensal bacterium and a prominent cause of infections globally. The high incidence of S. aureus infections is compounded by the ability of the microbe to readily acquire resistance to antibiotics.
Scott D. Kobayashi, James M. Musser, Frank R. DeLeo   +2 more
doaj   +1 more source

One More Disguise in the Stealth Behavior of Streptococcus pyogenes

mBio, 2016
The ability to hide in the animal kingdom is essential for survival; the same is true for bacteria. Streptococcus pyogenes is considered one of the more successful stealth bacteria in its production of a hyaluronic acid capsule that is chemically ...
Vincent A. Fischetti, James B. Dale
doaj   +1 more source

Bacterial Pathogenesis and Antibacterial Control

, 2018
Bacterial pathogens have been becoming the main problem in hospital and community-acquired infections. It is hard to treat the strains that are resistant to antibiotics, due to the causing recurrent and untreatable infections.

core   +1 more source

Pseudomonas aeruginosa MipA-MipB envelope proteins act as new sensors of polymyxins

mBio
Due to the rising incidence of antibiotic-resistant infections, the last-line antibiotics, polymyxins, have resurged in the clinics in parallel with new bacterial strategies of escape.
Manon Janet-Maitre, Viviana Job, Maxime Bour, Mylène Robert-Genthon, Sabine Brugière, Pauline Triponney, David Cobessi, Yohann Couté, Katy Jeannot, Ina Attrée   +9 more
doaj   +1 more source

Bacterial-epithelial contact is a key determinant of host innate immune responses to enteropathogenic and enteroaggregative escherichia coli [PDF]

, 2011
Background: Enteropathogenic (EPEC) and Enteroaggregative (EAEC) E. coli have similar, but distinct clinical symptoms and modes of pathogenesis. Nevertheless when they infect the gastrointestinal tract, it is thought that their flagellin causes IL-8 ...
Nigel J Klein, Simon H Murch, Edwards Lindsey A., Klein, Nigel J, Phillips, Alan D., Edwards, LA, Phillips, AD, Simon H. Murch, Edwards, Lindsey A., Phillips, Alan D, Mona Bajaj-Elliott, Lindsey A Edwards, Alan D. Phillips, Murch, SH, Bajaj-Elliott, Mona, Alan D Phillips, Klein Nigel J., Murch Simon H., Nigel J. Klein, Klein, NJ, Phillips Alan D., Klein, Nigel, Lindsey A. Edwards, Murch, Simon H, Bajaj-Elliott, M, Murch, Simon, Bajaj-Elliott Mona, Edwards, Lindsey A; id_orcid   +27 more
core   +1 more source

Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa

Frontiers in Microbiology, 2019
The type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the polymerization of a 9-
Charlotte Lombardi, James Tolchard, Stephanie Bouillot, Luca Signor, Caroline Gebus, David Liebl, Daphna Fenel, Jean-Marie Teulon, Juliane Brock, Birgit Habenstein, Jean-Luc Pellequer, Eric Faudry, Antoine Loquet, Ina Attrée, Andréa Dessen, Andréa Dessen, Viviana Job, Viviana Job   +17 more
doaj   +1 more source

Roles of host SUMOylation in bacterial pathogenesis. [PDF]

Infect Immun, 2023
Ma X, Zhao C, Xu Y, Zhang H.
europepmc   +1 more source

Transcriptional diversification in a human-adapting zoonotic pathogen drives niche-specific evolution

Nature Communications
Bacterial pathogens can undergo striking adaptive evolutionary change in the context of infection, driven by selection forces associated with host defenses and antibiotic treatment.
Soma Ghosh, Chao-Jung Wu, Abraham G. Moller, Adrien Launay, Laina N. Hall, Bryan T. Hansen, Elizabeth R. Fischer, Jung-Ho Youn, Pavel P. Khil, John P. Dekker   +9 more
doaj   +1 more source

Hypoxia drives progression of multiple sclerosis by enhancing the inflammasome activation in macrophages with Porphyromonas gingivalis infection

Cell Death Discovery
Porphyromonas gingivalis (Pg), a gram-negative anaerobic bacterium, is a leading pathogen causing periodontitis. It secretes several virulence factors, including gingipains, lipopolysaccharides (LPS), and outer membrane vesicles (OMVs), which can trigger
Tokuju Okano, Hiroshi Ashida, Masayuki Tsukasaki, Tamako Iida, Masahiro Yamamoto, Hiroshi Takayanagi, Takeharu Sakamoto, Toshihiko Suzuki   +7 more
doaj   +1 more source

The Role of Bacteriophage-Derived Small RNA Molecules in Bacterial and Phage Interactions

Small regulatory RNAs (sRNAs) play a critical role in bacterial gene expression, modulating various cellular processes, including stress responses, metabolism, virulence, and many others.
Wojciech Wesołowski, Grzegorz Węgrzyn, Bożena Nejman-Faleńczyk, Aleksandra Łukasiak, Sylwia Bloch, Natalia Lewandowska   +5 more
core   +1 more source