Results 161 to 170 of about 1,657,824 (211)

Glycointeractions in Bacterial Pathogenesis

Nature Reviews Microbiology, 2018
Many important interactions between bacterial pathogens and their hosts are highly specific binding events that involve host or pathogen carbohydrate structures (glycans). Glycan interactions can mediate adhesion, invasion and immune evasion and can act as receptors for toxins.
Mark von Itzstein, Christopher J Day, James Paton   +2 more
exaly   +5 more sources

Bacterial Biopolymers: From Pathogenesis to Advanced Materials

Nature Reviews Microbiology, 2020
Bacteria are prime cell factories that can efficiently convert carbon and nitrogen sources into a large diversity of intracellular and extracellular biopolymers, such as polysaccharides, polyamides, polyesters, polyphosphates, extracellular DNA and ...
Bernd Rehm, M Fata Moradali
exaly   +2 more sources

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Proteases in bacterial pathogenesis

Research in Microbiology, 2009
Bacterial pathogens rely on proteolysis for protein quality control under adverse conditions experienced in the host, as well as for the timely degradation of central virulence regulators. We have focused on the contribution of the conserved Lon, Clp, HtrA and FtsH proteases to pathogenesis and have highlighted common biological processes for which ...
Ingmer, Hanne, Brøndsted, Lone
openaire   +3 more sources

Evolution of bacterial pathogenesis

Cellular and Molecular Life Sciences (CMLS), 1999
The evolution of bacteria is associated with continuous generation of novel genetic variants. The major driving forces in this process are point mutations, genetic rearrangements, and horizontal gene transfer. A large number of human and animal bacterial pathogens have evolved the capacity to produce virulence factors that are directly involved in ...
W, Ziebuhr, K, Ohlsen, H, Karch, T, Korhonen, J, Hacker   +4 more
openaire   +2 more sources

Pathogenesis of Bacterial Endocarditis

JAMA: The Journal of the American Medical Association, 1963
SEVERAL ENIGMAS about the mechanism of valvular endocarditis still exist. Why such an entity prevails at all requires elucidation. The relation of vegetations on the valve to an underlying interstitial valvulitis and of the bacterial to the nonbacterial vegetation is still moot. Do the bacteria reach the valve via the interstitial capillary bed or as a
A A, ANGRIST, M, OKA
openaire   +2 more sources

PATHOGENESIS OF BACTERIAL MENINGITIS

Infectious Disease Clinics of North America, 1999
Bacterial meningitis is fatal in 5% to 40% of patients and causes neurologic sequelae in up to 30% of survivors. Much has been learned recently about the mechanisms that lead to brain injury during meningitis. Once bacteria have gained access to the central nervous system, their multiplication triggers a complex host response consisting of humoral and ...
Leib, Stephen, Täuber, Martin G.
openaire   +4 more sources

Bacterial phospholipases and pathogenesis

Microbes and Infection, 1999
Phospholipases are produced from a diverse group of bacterial pathogens causing very different diseases. In some cases, secreted phospholipases appear to be the major cause of pathophysiological effects. Yet in other cases, phospholipases are key virulence factors, contributing to bacterial survival or dissemination without causing tissue destruction ...
D H, Schmiel, V L, Miller
openaire   +2 more sources

Pathogenesis of Bacterial Diarrheas

New England Journal of Medicine, 1971
NO less than a renaissance has emerged in studies of diarrhea, in spite of the unattractive attributes of feces, the difficulty in identifying pathogens among a sea of other bacteria, and the conse...
G F, Grady, G T, Keusch
openaire   +2 more sources

Mn 2+ and bacterial pathogenesis

Frontiers in Bioscience, 2004
Fe2+ has traditionally been considered the most important divalent cation involved in host-pathogen interactions. However, recent research indicates a previously unappreciated role for transition metal divalent cations other than Fe2+ during infection.
Michelle L, Zaharik, B Brett, Finlay
openaire   +2 more sources

Bacterial Endotoxins and Pathogenesis

Clinical Infectious Diseases, 1983
Recent advances in endotoxin biochemistry, cell biology, and immunopathology are reviewed. Discussion is focused on the endotoxin-unresponsive C3H/HeJ mouse and the contributions the studies of this mouse have made to current concepts of the mechanisms of endotoxin action.
openaire   +2 more sources