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Salmonella: A Model for Bacterial Pathogenesis
Annual Review of Medicine, 2001▪ Abstract Salmonellae are gram-negative bacteria that cause gastroenteritis and enteric fever. Salmonella virulence requires the coordinated expression of complex arrays of virulence factors that allow the bacterium to evade the host's immune system. All Salmonella serotypes share the ability to invade the host by inducing their own uptake into cells
M E, Ohl, S I, Miller
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2000
Abstract De Bary’s (1879) broad definition of symbiosis includes parasitism and disease, areas in which significant discoveries are being made. This has been most evident in bacterial pathogenesis. In this chapter we introduce some of the recent findings of molecular mechanisms of bacterial pathogens.
Surindar Paracer, Vernon Ahmadjian
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Abstract De Bary’s (1879) broad definition of symbiosis includes parasitism and disease, areas in which significant discoveries are being made. This has been most evident in bacterial pathogenesis. In this chapter we introduce some of the recent findings of molecular mechanisms of bacterial pathogens.
Surindar Paracer, Vernon Ahmadjian
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Nitrosothiols in Bacterial Pathogens and Pathogenesis
Antioxidants & Redox Signaling, 2013The formation and degradation of S-nitrosothiols (SNOs) are important mechanisms of post-translational protein modification and appear to be ubiquitous in biology. These processes play well-characterized roles in eukaryotic cells, including a variety of pathologies and in relation to chronic conditions. We know little of the roles of these processes in
Laver, Jay R. +5 more
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Bacterial Infection and the Pathogenesis of COPD
Chest, 2000Bacterial infection of the lower respiratory tract can impact on the etiology, pathogenesis, and the clinical course of COPD in several ways. Several recent cohort studies suggest that lung growth is impaired by childhood lower respiratory tract infection, making these individuals more vulnerable to developing COPD on exposure to additional injurious ...
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The Pathogenesis of Gastrointestinal Bacterial Overgrowth
Chemotherapy, 2005The normal indigenous intestinal microflora consists of about 10<sup>15</sup> bacteria that under physiological conditions reside mainly in the lower gastrointestinal tract. Bacterial overgrowth implies abnormal bacterial colonization of the upper gut, resulting from failure of specific defense mechanisms restricting colonization under ...
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2019
This chapter focuses on bacterial pathogenesis. Most of the bacteria that colonize our bodies do so without causing us any harm. However, some bacteria are inherently more damaging than others. Their degree of pathogenicity is described in the term ‘virulence’, which can be quantified by establishing experimental metrics such as median lethal dose and ...
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This chapter focuses on bacterial pathogenesis. Most of the bacteria that colonize our bodies do so without causing us any harm. However, some bacteria are inherently more damaging than others. Their degree of pathogenicity is described in the term ‘virulence’, which can be quantified by establishing experimental metrics such as median lethal dose and ...
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Bacterial Virulence and Pathogenesis: An Overview
Clinical Infectious Diseases, 1983Bacterial virulence is the result of many different attributes, which often contribute to different steps in the complicated series of events we recognize as infection. With the use of selected examples, an overview of the stages of infection common to many bacterial infections (attachment, proliferation, tissue damage, invasion, and dissemination) is ...
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Adherent Bacterial Colonization in the Pathogenesis of Osteomyelitis
Science, 1985Direct scanning electron microscopy of material obtained during surgical debridement of osteomyelitic bone showed that the infecting bacteria grew in coherent microcolonies in an adherent biofilm so extensive it often obscured the infected bone surfaces. Transmission electron microscopy showed this biofilm to have a fibrous matrix, to contain some host
A G, Gristina +3 more
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Update on bacterial pathogenesis in BRD
Animal Health Research Reviews, 2009AbstractMannheimia haemolytica, Pasteurella multocida, Histophilus somni, Mycoplasma bovis and Arcanobacterium pyogenes are all frequently implicated in bovine respiratory disease (BRD). M. haemolytica is considered the most important of the group. These bacteria are commensals in the nasopharynx and establish infection in the lungs of cattle that are ...
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Cytokines in the pathogenesis of bacterial meningitis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991Adjunctive dexamethasone therapy to antibiotic therapy for bacterial meningitis has been shown in several studies to be beneficial. The roles of interleukin 1 beta and tumour necrosis factor alpha (TNF-alpha) in bacterial meningitis and in an experimental rabbit model are reviewed; both cytokines play a pivotal role in induction of meningitis.
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