Results 51 to 60 of about 4,861 (201)

Beyond bacterial defences: the role of lysozyme in cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang   +4 more
wiley   +1 more source

Efeito antimicrobiano de dois medicamentos endodônticos com diferentes exposições, e as alterações morfológicas causadas a Enterococcus faecalis [PDF]

open access: yes, 2011
PURPOSE: The aim of this study was to verify the antimicrobial effect of calcium hydroxide and iodoform on Enterococcus faecalis with different exposure times evaluating the bacterial morphologic alterations.
Carreira, Karine   +5 more
core   +3 more sources

Dual‐function, Reusable, and Flexible Thermal Interface for Kinetic Monitoring of In Vitro Bioassays

open access: yesSmall Methods, Volume 10, Issue 3, 9 February 2026.
This work presents a reusable, dual‐function thermal interface for non‐contact, label‐free sensing and microwell‐independent temperature control in microplates within a single element. Real‐time monitoring of E. coli growth and the response to antibiotic treatment demonstrates the sensor's enhanced sensitivity in interface‐dominated processes compared ...
Daniel Nieder   +4 more
wiley   +1 more source

Cyclic di-AMP Is Critical for Listeria monocytogenes Growth, Cell Wall Homeostasis, and Establishment of Infection

open access: yesmBio, 2013
Listeria monocytogenes infection leads to robust induction of an innate immune signaling pathway referred to as the cytosolic surveillance pathway (CSP), characterized by expression of beta interferon (IFN-β) and coregulated genes.
Chelsea E. Witte   +5 more
doaj   +1 more source

Contributions of the pore-forming toxin Listeriolysin O to Listeria monocytogenes pathogenesis [PDF]

open access: yes, 2019
Listeriolysin O (LLO) is an essential determinant of Listeria monocytogenes pathogenesis that mediates the escape of L. monocytogenes from host cell vacuoles, thereby allowing replication in the cytosol without causing appreciable cell death. As a member
Nguyen, Brittney Nhu-Chau
core  

Transgenic Tobacco Plants Expressing Synthetic Peptides: A Functional and Structural Analysis for Pathogen Resistance

open access: yesPlant Biotechnology Journal, Volume 24, Issue 2, Page 526-546, February 2026.
Peptide Power: VR18 & KG18 Shield Tobacco from Bacterial Attack. A schematic shows how antimicrobial peptides VR18 and KG18 fight Pseudomonas syringae—bursting bacterial membranes and boosting disease resistance in transgenic tobacco, without harming plant health.
Karishma Biswas   +17 more
wiley   +1 more source

Viral warriors: Screening water samples for bacteriophages against multiple drug resistant bacteria [PDF]

open access: yes, 2016
Although mutation occurs randomly in nature and is passed randomly between bacterial species, the misuse and overuse of antibiotics in modern medicine has selected for antibiotic resistant organisms, resulting in an epidemic of antibiotic resistant ...

core  

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du   +5 more
wiley   +1 more source

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 1, Page 235-244, January 2026.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu   +3 more
wiley   +1 more source

Mechanistic Insights Into Protein Aggregation Inhibition by Green‐Synthesized Silver Nanoparticles: A Study on Human Lysozyme

open access: yesIET Nanobiotechnology, Volume 2026, Issue 1, 2026.
A characteristic of many neurodegenerative disorders, such as Parkinson’s and Alzheimer’s, is amyloidogenic protein aggregation, for which there are currently no proven cures. Aging, mutation, and physiological stress can cause proteins to deviate from their natural folding patterns, potentially leading to the formation of hazardous protein aggregates.
Md. Tauqir Alam   +4 more
wiley   +1 more source

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