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The growth of bacteriophage [PDF]

open access: yesJournal of General Physiology, 1939
1. An anti-Escherichia coli phage has been isolated and its behavior studied. 2. A plaque counting method for this phage is described, and shown to give a number of plaques which is proportional to the phage concentration.
Delbrück, Max, Ellis, Emory L.
core   +8 more sources

Social Bacteriophages [PDF]

open access: yesMicroorganisms, 2020
Despite their simplicity, viruses can display social-like interactions such as cooperation, communication, and cheating. Focusing on bacteriophages, here we review features including viral product sharing, cooperative evasion of antiviral defenses, prudent host exploitation, superinfection exclusion, and inter-phage peptide-mediated signaling. We argue
Pilar Domingo-Calap   +2 more
openaire   +4 more sources

Pharokka: a fast scalable bacteriophage annotation tool

open access: yesBioinform., 2022
Summary In recent years, there has been an increasing interest in bacteriophages, which has led to growing numbers of bacteriophage genomic sequences becoming available.
G. Bouras   +5 more
semanticscholar   +1 more source

Design of bacteriophage T4-based artificial viral vectors for human genome remodeling

open access: yesNature Communications, 2023
Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter human cells and carry out molecular repairs will have broad applications.
Jingen Zhu   +8 more
doaj   +1 more source

Bacteriophage T4 Escapes CRISPR Attack by Minihomology Recombination and Repair

open access: yesmBio, 2021
Bacteriophages (phages) are viruses that infect bacteria and use them as replication factories to assemble progeny phages. Bacteria have evolved powerful defense mechanisms to destroy the invading phages by severing their genomes soon after entry into ...
Xiaorong Wu   +3 more
doaj   +1 more source

Campylobacter bacteriophages and bacteriophage therapy [PDF]

open access: yesJournal of Applied Microbiology, 2011
Members of the genus Campylobacter are frequently responsible for human enteric disease with occasionally very serious outcomes. Much of this disease burden is thought to arise from consumption of contaminated poultry products. More than 80% of poultry in the UK harbour Campylobacter as a part of their intestinal flora.
Ian F. Connerton   +2 more
openaire   +3 more sources

Animal Models in the Evaluation of the Effectiveness of Phage Therapy for Infections Caused by Gram-Negative Bacteria from the ESKAPE Group and the Reliability of Its Use in Humans

open access: yesMicroorganisms, 2021
The authors emphasize how extremely important it is to highlight the role played by animal models in an attempt to determine possible phage interactions with the organism into which it was introduced as well as to determine the safety and effectiveness ...
Martyna Cieślik   +3 more
doaj   +1 more source

Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae

open access: yesNature Communications, 2022
A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is treated with a pre-adapted bacteriophage along with meropenem and colistin, followed by ceftazidime ...
Anaïs Eskenazi   +17 more
semanticscholar   +1 more source

Engineering bacteriophages for enhanced host range and efficacy: insights from bacteriophage-bacteria interactions

open access: yesFrontiers in Microbiology, 2023
Bacteriophages, the most abundant organisms on earth, have the potential to address the rise of multidrug-resistant bacteria resulting from the overuse of antibiotics. However, their high specificity and limited host range can hinder their effectiveness.
Huang-Jie Jia   +5 more
semanticscholar   +1 more source

Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response

open access: yesCells, 2021
Studies described so far suggest that human β-defensin 2 is an important protein of innate immune response which provides protection for the human organism against invading pathogens of bacterial, viral, fungal, as well as parasitical origin. Its pivotal
Martyna Cieślik   +3 more
doaj   +1 more source

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