Results 1 to 10 of about 298,587 (264)

Ion-dependent dynamics of DNA ejections for bacteriophage lambda [PDF]

, 2010
We study the control parameters that govern the dynamics of in vitro DNA ejection in bacteriophage lambda. Past work has demonstrated that bacteriophage DNA is highly pressurized; this pressure has been hypothesized to help drive DNA ejection.
Arkin, Brewer, Catalano, Chiaruttini, Comolli, David Van Valen, David Wu, Dodd, Esquinas-Rychen, Evilevitch, Evilevitch, Evilevitch, Evilevitch, Fang, Fuller, Fuller, Grayson, Grayson, Han, Hershey, Hud, Jeembaeva, Johnson, Joly, Keller, Kindt, Leforestier, Leforestier, Leforestier, Li, Mangenot, Marko, Michel, Molineux, Novick, Odijk, Oppenheim, Petrov, Petrov, Purohit, Purohit, Qicong Hu, Rau, Rob Phillips, Sambrook, Smith, Smith, Smith, St-Pierre, Stock, São-José, Tzlil, Zeng   +52 more
arxiv   +7 more sources

Evaluation of Microencapsulation of The UFV-AREG1 Bacteriophage in Alginate-Ca Microcapsules using Microfluidic Devices [PDF]

, 2017
The indiscriminate use of antibiotics and the emergence of resistant microorganisms have become a major challenge for the food industry. The purpose of this work was to microencapsulate the bacteriophage UFV-AREG1 in a calcium alginate matrix using microfluidic devices and to study the viability and efficiency of retention. The microcapsules were added
Batalha, Laís S., Boggionea, Delaine M. G., Gontijo, Marco T. P., Lopez, Maryoris E. S., Mendonça, Regina C. S., Santos, Igor J. B., Teixeira, Alvaro V. N. C.   +6 more
arxiv   +4 more sources

ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis [PDF]

Nature Communications, 2018
peer-reviewedCrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to infect bacteria of the order Bacteroidales. Despite being found in ~50% of individuals and representing up to 90% of human gut viromes, members of this
Draper, Lorraine A., Fitzgerald, C. Brian, Hill, Colin, Khokhlova, Ekaterina V., Ross, R Paul, Shkoporov, Andrey N., Stockdale, Stephen R.   +6 more
core   +5 more sources

Forces During Bacteriophage DNA Packaging and Ejection [PDF]

, 2004
The conjunction of insights from structural biology, solution biochemistry, genetics and single molecule biophysics has provided a renewed impetus for the construction of quantitative models of biological processes. One area that has been a beneficiary of these experimental techniques is the study of viruses.
Arsuaga, Baker, Bednar, Black, Bohm, Booy, Castelnovo, Cerritelli, Cordova, de Vries, Dokland, Earnshaw, Echols, Endy, Evilevitch, Evilevitch, Feiss, Flint, Gabashvili, Gelbart, Hershey, Iwasaki, Jané Kondev, Kanamaru, Kindt, Klug, La Scola, LaMarque, Landau, Lata, Leiman, Letellier, Lyubartsev, Mandar M. Inamdar, Marenduzzo, Molineux, Nelson, Novick, Odijk, Odijk, Odijk, Odijk, Odijk, Parsegian, Paul D. Grayson, Prashant K. Purohit, Ptashne, Purohit, Purohit, Raspaud, Rau, Rau, Reddy, Richards, Riemer, Rob Phillips, Shibata, Simpson, Smith, Smith, Strey, Tama, Tao, Todd M. Squires, Tzlil, Young   +65 more
arxiv   +5 more sources

The effect of genome length on ejection forces in bacteriophage lambda [PDF]

arXiv, 2005
A variety of viruses tightly pack their genetic material into protein capsids that are barely large enough to enclose the genome. In particular, in bacteriophages, forces as high as 60 pN are encountered during packaging and ejection, produced by DNA bending elasticity and self-interactions. The high forces are believed to be important for the ejection
Evilevitch, Alex, Gelbart, William M., Grayson, Paul, Inamdar, Mandar M., Knobler, Charles M., Phillips, Rob, Purohit, Prashant K.   +6 more
arxiv   +5 more sources

Bacteriophage T4 Escapes CRISPR Attack by Minihomology Recombination and Repair

mBio, 2021
Bacteriophages (phages) are viruses that infect bacteria and use them as replication factories to assemble progeny phages. Bacteria have evolved powerful defense mechanisms to destroy the invading phages by severing their genomes soon after entry into ...
Xiaorong Wu, Jingen Zhu, Pan Tao, Venigalla B. Rao   +3 more
doaj   +1 more source

Design of bacteriophage T4-based artificial viral vectors for human genome remodeling

Nature Communications, 2023
Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter human cells and carry out molecular repairs will have broad applications.
Jingen Zhu, Himanshu Batra, Neeti Ananthaswamy, Marthandan Mahalingam, Pan Tao, Xiaorong Wu, Wenzheng Guo, Andrei Fokine, Venigalla B. Rao   +8 more
doaj   +1 more source

Animal Models in the Evaluation of the Effectiveness of Phage Therapy for Infections Caused by Gram-Negative Bacteria from the ESKAPE Group and the Reliability of Its Use in Humans

Microorganisms, 2021
The authors emphasize how extremely important it is to highlight the role played by animal models in an attempt to determine possible phage interactions with the organism into which it was introduced as well as to determine the safety and effectiveness ...
Martyna Cieślik, Natalia Bagińska, Andrzej Górski, Ewa Jończyk-Matysiak   +3 more
doaj   +1 more source

Pharokka: a fast scalable bacteriophage annotation tool

Bioinform., 2022
Summary In recent years, there has been an increasing interest in bacteriophages, which has led to growing numbers of bacteriophage genomic sequences becoming available.
G. Bouras, Roshan Nepal, Ghais Houtak, A. Psaltis, P. Wormald, S. Vreugde   +5 more
semanticscholar   +1 more source

Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae

Nature Communications, 2022
A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is treated with a pre-adapted bacteriophage along with meropenem and colistin, followed by ceftazidime ...
Anaïs Eskenazi, C. Lood, Julia M. Wubbolts, M. Hites, N. Balarjishvili, Lika Leshkasheli, L. Askilashvili, L. Kvachadze, V. van Noort, J. Wagemans, Marc Jayankura, N. Chanishvili, M. D. de Boer, P. Nibbering, M. Kutateladze, R. Lavigne, M. Merabishvili, J. Pirnay   +17 more
semanticscholar   +1 more source