Results 91 to 100 of about 248,152 (310)
On the persistence of lytic bacteriophages in vivo and its consequences for bacteriophage therapy [PDF]
arXiv, 2019 Bacteriophages are viruses infecting bacteria and archaea. Many phage species cause infections which lead to the certain death of the infected prokaryotic host cell and the release of a large batch of phage progeny, yet they have been able to stably coexist with their bacterial hosts over the eons in nature, as well as in the majority of laboratory ...
arxiv
Advanced Materials Interfaces, EarlyView.Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler +4 more
wiley +1 more source
Coinfection in a stochastic model for bacteriophage systems [PDF]
arXiv, 2017 A system modeling bacteriophage treatments with coinfections in a noisy context is analyzed. We prove that in a small noise regime, the system converges in the long term to a bacteria free equilibrium. Moreover, we compare the treatment with coinfection with the treatment without coinfection, showing how the coinfection affects the dose of ...
arxiv
Self‐Assembled Physical Unclonable Function Labels Based on Plasmonic Coupling
Advanced Optical Materials, EarlyView.This article introduces advanced anti‐counterfeit labels crafted through DNA‐guided self‐assembly of plasmonic nanoparticles. Utilizing nanosphere lithography for dense and precise nanoparticle placement, these labels feature unique, unclonable optical signatures achieved through plasmonic coupling, detectable by an economical 3D‐printed dark field ...
Mihir Dass +9 more
wiley +1 more source
ELECTROPHORESIS, Volume 43, Issue 23-24, Page 2402-2427, December 2022., 2022 Abstract Nucleic acids are the blueprint of life. They are not only the construction plan of the single cell or higher associations of them, but also necessary for function, communication and regulation. Due to the pandemic, the attention shifted in particular to their therapeutic potential as a vaccine. As pharmaceutical oligonucleotides are unique in
Robert Minkner +3 more
wiley +1 more source
A stochastic model for bacteriophage therapies [PDF]
Math. Biosci. (2013) 99-108, 2011 In this article, we analyze a system modeling bacteriophage treatments for infections in a noisy context. In the small noise regime, we show that after a reasonable amount of time the system is close to a sane equilibrium (which is a relevant biologic information) with high probability.
arxiv
Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation. [PDF]
, 2017 Tailed bacteriophages and herpesviruses assemble infectious particles via an empty precursor capsid (or \u27procapsid\u27) built by multiple copies of coat and scaffolding protein and by one dodecameric portal protein.
Afonine, Pavel V. +7 more
core +2 more sources
Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model
Advanced Therapeutics, EarlyView.A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika +7 more
wiley +1 more source
BiomedicinesThe development of bacteriophages (phages) as active pharmaceutical ingredients for the treatment of patients is on its way and regulatory agencies are calling for reliable methods to assess phage potency.
Nicolas Dufour +2 more
doaj +1 more source
Effective elimination of Staphylococcal contamination from hospital surfaces by a bacteriophage-probiotic sanitation strategy: a monocentric study. [PDF]
, 2019 Persistent contamination of hospital surfaces and antimicrobial resistance (AMR) are recognized major causes of healthcare-associated infections (HAI). We recently showed that a probiotic-based sanitation (PCHS) can stably decrease surface pathogens and ...
BISI, Matteo +6 more
core +1 more source