Results 231 to 240 of about 336,180 (306)

Enhanced exonuclease–Cas9 systems promote multiple nucleotide deletions with higher efficiency and broader targeting scope in plants

Journal of Integrative Plant Biology, EarlyView.
Cas9 preferentially generates small indels. By tethering an exonuclease and a DNA‐binding domain (DBD) to Cas9, the Exo‐DBD‐Cas9 system efficiently promotes multiple nucleotide deletions. These expanded deletions enable effective disruption of miRNA‐mediated regulation and relieve translational repression through targeted editing of 3′ untranslated ...
Rui Zhang, Xu Tang, Yao He, Wei Wang, Qiurong Ren, Yiping Qi, Yong Zhang   +6 more
wiley   +1 more source

A Lytic Bacteriophage as a Potential Biocontrol Agent Against Avian Enterotoxigenic <i>Escherichia coli</i> Associated With Colibacillosis. [PDF]

Can J Infect Dis Med Microbiol
Sasoon A, Nikkhahi F, Kiaheyrati N, Javadi A, Peymani A, Sanei AF, Fardsanei F.   +6 more
europepmc   +1 more source

Synergistic engineering of Casδ nuclease for robust genome editing

Journal of Integrative Plant Biology, EarlyView.
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge, Chenchen Peng, Yang Du, Ying Chen, Zilong Zhao, Meixia Yu, Huairu Feng, Yuyang Xie, Siwei Sun, Shengnan Liu, Beibei Xin, Haiming Zhao, Sen Wu, Chao Bian, Zhijia Yang, Jinsheng Lai, Jian Chen   +16 more
wiley   +1 more source

Isolation and characterization of novel lytic bacteriophages against (fluoro)quinolone-resistant <i>Campylobacter</i> strains. [PDF]

Front Microbiol
Calancha-Padrón YE, Perez-Condori D, Gutierrez-Valverde MF, Salas-Veizaga DM, Hjort K, Alvarez-Aliaga MT.   +5 more
europepmc   +1 more source

SIB1‐SEC23A undergo ER to chloroplast relocalization to mediate immunity in Arabidopsis thaliana

Journal of Integrative Plant Biology, EarlyView.
SEC23A mediates membrane trafficking between the endoplasmic reticulum (ER) and Golgi apparatus and interacts with the immunity protein SIGMA FACTOR‐BINDING PROTEIN1 in Arabidopsis. Under stress, both proteins relocate from the ER to chloroplasts, suppressing photosynthesis genes and enhancing defense genes.
Jialin Peng, Huan Zhong, Jianan Zhang, Hailei Zhang, Wuzhen Liu, Yonglun Zeng, Liwen Jiang, Yiji Xia   +7 more
wiley   +1 more source

Antibacterial Activity of Bacteriophage Lytic Enzyme Ply900. [PDF]

Vet Sci
Li Y, Xu L, Zhang Y, Dong C, Zhou H.
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Case Report: Bacteriophage-antibiotic therapy for extensively drug-resistant <i>Acinetobacter baumannii</i> in critically ill patient with respiratory infection. [PDF]

Front Med (Lausanne)
Lin J, Dai G, Zhang L, Xu P, Zhao P, Zhou Y, Lu H, Zheng M.   +7 more
europepmc   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Genome of Myoviridae Phage Lethe Isolated In Northern Georgia. [PDF]

MicroPubl Biol
Alexander P, Blair M, Boyen E, Bumgarner L, Grogan G, Lesperance E, Kanak A.   +6 more
europepmc   +1 more source