Results 221 to 230 of about 285,810 (297)

Engineering Carbon Nanotube Quantum Well Defects With Recognition Tripeptides for Optical Detection of Extracellular Vesicles in Plasma

open access: yesSmall, EarlyView.
A three‐residue peptide bioconjugated onto a carbon nanotube quantum defect turns the near‐infrared emission of quantum defects into a reporter of integrins on intact extracellular vesicles, directly in human plasma. The sensor reveals that healthy fibroblast vesicles carry as much RGD‐binding integrin as cancer‐derived ones, an adhesion‐associated ...
In‐Jun Hwang   +9 more
wiley   +1 more source

High‐Throughput FRET Affinity Screening Technique (HTFAST) for Cell‐Free Expressed Binding Protein Characterization

open access: yesSmall, EarlyView.
High‐Throughput FRET Affinity Screening Technique (HTFAST) for quantitative, purification‐free affinity screening of cell‐free expressed binders. A fluorescent‐protein‐fused binder (donor) is expressed directly in crude E. coli cell‐free lysate and titrated against a dye‐labeled antigen (acceptor).
Sepehr Hejazi   +5 more
wiley   +1 more source

Asymptotic r2 Enhancement in Formulation‐Optimized Lipid‐Iron Oxide Nanoparticles for Assessing Glioblastoma Heterogeneity at Ultrahigh‐Field MRI

open access: yesSmall, EarlyView.
Lipid‐coated superparamagnetic iron oxide nanoparticles (LSPIONs) are developed as MRI‐visible lipid nanocarriers for glioblastoma imaging. By tuning nanoparticle size and SPION loading, their transverse relaxivity (r2) can be systematically controlled over one order of magnitude, reaching 390 mm−1 s−1 at 9.4 T.
Marcos Bazarra‐Barreiros   +8 more
wiley   +1 more source

Biocontrol of Staphylococcus aureus in dairy products using lytic bacteriophage UHP46: efficacy in milk, cheese, and yogurt. [PDF]

open access: yesBraz J Microbiol
Najeeb S   +7 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

open access: yesSmall Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo   +7 more
wiley   +1 more source

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