Results 41 to 50 of about 131,877 (321)
Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022 Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem +6 more
wiley +1 more source
Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Next‐generation diagnostics: Nanocarbon‐based field effect transistors (NC‐FETs) use incoming target analytes to impart a gating effect on conductance. Here, we review the operational mechanisms behind NC‐FETs, the fabrication and functionalisation of NC‐FETs with receptor biomolecules and downstream biosensing applications.
Chang‐Seuk Lee +4 more
wiley +1 more source
Scientific Reports, 2021 Bacteriophages are bacterial viruses and the most abundant biological entities on Earth. Temperate bacteriophages can form prophages stably maintained in the host population: they either integrate into the host genome or replicate as plasmids in the host
Emma G. Piligrimova +6 more
doaj +1 more source
What Are the Potential Benefits of Using Bacteriophages in Periodontal Therapy?
Antibiotics, 2022 Periodontitis, which may result in tooth loss, constitutes both a serious medical and social problem. This pathology, if not treated, can contribute to the development of, among others, pancreatic cancer, cardiovascular diseases or Alzheimer’s disease ...
Jan Kowalski +4 more
doaj +1 more source
Highly Sensitive Bacteriophage-Based Detection of Brucella abortus in Mixed Culture and Spiked Blood
Viruses, 2017 For decades, bacteriophages (phages) have been used for Brucella species identification in the diagnosis and epidemiology of brucellosis. Traditional Brucella phage typing is a multi-day procedure including the isolation of a pure culture, a step that ...
Kirill V. Sergueev +2 more
doaj +1 more source
Bacteriophage effect on parasitism resistance [PDF]
arXiv, 2022 Many studies have shown that the protection of the host $\it{Acyrthosiphon~pisum}$ (Hemiptera, Aphididae) against the parasitoid $\it{Aphidius~ervi}$ (Hymenoptera, Braconidae) is conferred by the interaction between the secondary endosymbiont $\it{Hamiltonella~defensa}$ and the bacteriophage $\it{APSE}$ ($\it{Acyrthosiphon~pisum}$ secondary ...
arxiv
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
A mechanical model of bacteriophage DNA ejection [PDF]
, 2017 Single molecule experiments on bacteriophages show an exponential scaling for the dependence of mobility on the length of DNA within the capsid. It has been suggested that this could be due to the "capstan mechanism" -- the exponential amplification of friction forces that result when a rope is wound around a cylinder as in a ship's capstan.
arxiv +1 more source
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
FEBS Open Bio, EarlyView.With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet +6 more
wiley +1 more source
The Appearance of Antiphage Antibodies in Sera of Patients Treated with Phages
AntibioticsBackground: Bacteriophages are neutralized by the sera of patients undergoing phage therapy (PT), particularly during local or concomitant local and oral phage administration in bone infections, soft tissue infections, or upper respiratory tract ...
Marzanna Łusiak-Szelachowska +4 more
doaj +1 more source