Results 21 to 30 of about 20,664 (176)
Molecular Modeling the Proteins from the exo-xis Region of Lambda and Shigatoxigenic Bacteriophages
Antibiotics, 2021 Despite decades of intensive research on bacteriophage lambda, a relatively uncharacterized region remains between the exo and xis genes. Collectively, exo-xis region genes are expressed during the earliest stages of the lytic developmental cycle and are
Logan W. Donaldson
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F1000Research, 2013 Genetic manipulation in enterohemorrhagic E. coli O157:H7 is currently restricted to recombineering, a method that utilizes the recombination system of bacteriophage lambda, to introduce gene replacements and base changes inter alia into the genome ...
Martin G Marinus, Anthony R Poteete
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Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages
Frontiers in Microbiology, 2021 Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages).
Ann-Katrin Llarena +4 more
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Canine hepacivirus NS3 serine protease can cleave the human adaptor proteins MAVS and TRIF. [PDF]
PLoS ONE, 2012 Canine hepacivirus (CHV) was recently identified in domestic dogs and horses. The finding that CHV is genetically the virus most closely related to hepatitis C virus (HCV) has raised the question of whether HCV might have evolved as the result of close ...
Mariona Parera +4 more
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An Optimal Lysis Time Maximizes Bacteriophage Fitness in Quasi-Continuous Culture
mBio, 2022 Optimality models have a checkered history in evolutionary biology. While optimality models have been successful in providing valuable insight into the evolution of a wide variety of biological traits, a common objection is that optimality models are ...
Sherin Kannoly +2 more
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Restriction alleviation by bacteriophages lambda and lambda reverse [PDF]
Journal of Virology, 1981 Deletion analysis indicated that the phage lambda restriction alleviation gene(s) ral resides between the cIII and N genes. The Ral+ phenotype was expressed only when lambda ral+ carried a modification such that it was resistant to restriction by the host specificity system.
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Roles of orf60a and orf61 in Development of Bacteriophages λ and Φ24B
Viruses, 2018 The exo-xis region of lambdoid bacteriophage genomes contains several established and potential genes that are evolutionarily conserved, but not essential for phage propagation under laboratory conditions.
Aleksandra Dydecka +7 more
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Cell fate decisions emerge as phages cooperate or compete inside their host
Nature Communications, 2017 The bacteriophage lambda and its hostEscherichia coli provide a model system to study cell-fate decisions. Here, Trinh et al. develop a four-colour fluorescence system at the single-cell/single-virus/single-viral-DNA level and find phages cooperate ...
Jimmy T. Trinh +4 more
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Lambda-Display: A Powerful Tool for Antigen Discovery
Molecules, 2011 Since its introduction in 1985, phage display technology has been successfully used in projects aimed at deciphering biological processes and isolating molecules of practical value in several applications.
Nicola Gargano, Elisa Beghetto
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eLife, 2016 The molecular machinery responsible for DNA expression, recombination, and compaction has been difficult to visualize as functionally complete entities due to their combinatorial and structural complexity.
Gurunathan Laxmikanthan +9 more
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