Results 31 to 40 of about 169,837 (200)

Restriction alleviation by bacteriophages lambda and lambda reverse [PDF]

Journal of Virology, 1981
Deletion analysis indicated that the phage lambda restriction alleviation gene(s) ral resides between the cIII and N genes. The Ral+ phenotype was expressed only when lambda ral+ carried a modification such that it was resistant to restriction by the host specificity system.
openaire   +2 more sources

Roles of orf60a and orf61 in Development of Bacteriophages λ and Φ24B

Viruses, 2018
The exo-xis region of lambdoid bacteriophage genomes contains several established and potential genes that are evolutionarily conserved, but not essential for phage propagation under laboratory conditions.
Aleksandra Dydecka, Bożena Nejman-Faleńczyk, Sylwia Bloch, Gracja Topka, Agnieszka Necel, Logan W. Donaldson, Grzegorz Węgrzyn, Alicja Węgrzyn   +7 more
doaj   +1 more source

Cell fate decisions emerge as phages cooperate or compete inside their host

Nature Communications, 2017
The bacteriophage lambda and its hostEscherichia coli provide a model system to study cell-fate decisions. Here, Trinh et al. develop a four-colour fluorescence system at the single-cell/single-virus/single-viral-DNA level and find phages cooperate ...
Jimmy T. Trinh, Tamás Székely, Qiuyan Shao, Gábor Balázsi, Lanying Zeng   +4 more
doaj   +1 more source

Lambda-Display: A Powerful Tool for Antigen Discovery

Molecules, 2011
Since its introduction in 1985, phage display technology has been successfully used in projects aimed at deciphering biological processes and isolating molecules of practical value in several applications.
Nicola Gargano, Elisa Beghetto
doaj   +1 more source

Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]

, 2011
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nejman, Bożena, Nadratowska-Wesołowska, Beata, Węgrzyn, Alicja, Węgrzyn, Grzegorz, Szalewska-Pałasz, Agnieszka   +4 more
core   +1 more source

Genetic recombination in bacteriophage lambda [PDF]

, 2016
Bacteriophage λ (lambda) infects Escherichia coli and induces a dramatically increased rate and altered profile of genetic recombination as part of the cycle of infection.

core   +1 more source

Regulatory network of bacteriophage lambda.

, 2014
Left: Genes and operators which are involved in lysogenic and lytic process of bacteriophage Lambda. Right: Simplified regulatory network of and in bacteriophage lambda.
Ali Sharifi-Zarchi (608691), Hamid Mahini (608690), Mehdi Sadeghi (63721), Ruzbeh Tusserkani (608693), Faezeh Dorri (608689), Mehdi Totonchi (608692), Hamid Pezeshk (63720)   +6 more
core   +1 more source

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

Angewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee, Letizia Dondi, Amal Mathai, Connor Nurmi, Yingfu Li   +4 more
wiley   +2 more sources

Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction

eLife, 2016
The molecular machinery responsible for DNA expression, recombination, and compaction has been difficult to visualize as functionally complete entities due to their combinatorial and structural complexity.
Gurunathan Laxmikanthan, Chen Xu, Axel F Brilot, David Warren, Lindsay Steele, Nicole Seah, Wenjun Tong, Nikolaus Grigorieff, Arthur Landy, Gregory D Van Duyne   +9 more
doaj   +1 more source

Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids [PDF]

, 2007
The bacteriophage phi29 generates large forces to compact its double-stranded DNA genome into a protein capsid by means of a portal motor complex. Several mechanical models for the generation of these high forces by the motor complex predict coupling of ...
Hetherington, Craig L., Craig L Hetherington, Falk, Wayne, Wayne Falk, Thorsten Hugel, Jardine, Paul J., Falk Wayne, Hugel Thorsten, Bustamante, Carlos, Grimes Shelley, Michaelis, Jens, Walter Jessica M, Bustamante Carlos, Michaelis Jens, Anderson, Dwight L., Hugel, Thorsten, Grimes, Shelley, Paul J Jardine, Jessica M Walter, Walter, Jessica M., Jardine Paul J, Dwight L Anderson, Jens Michaelis, Anderson Dwight L, Carlos Bustamante, Hetherington Craig L, Shelley Grimes   +26 more
core   +1 more source