Mapping the tail fiber as the receptor binding protein responsible for differential host specificity of Pseudomonas aeruginosa bacteriophages PaP1 and JG004. [PDF]
, 2013 The first step in bacteriophage infection is recognition and binding to the host receptor, which is mediated by the phage receptor binding protein (RBP). Different RBPs can lead to differential host specificity.
He, Xuesong +7 more
core +2 more sources
Bacteriophages as an Up-and-Coming Alternative to the Use of Sulfur Dioxide in Winemaking [PDF]
, 2020 Certain acetic and lactic acid bacteria are major causes of quality defects in musts and wines, giving rise to defects such as a "vinegary," "sharp, like nail polish-remover" taste or preventing alcoholic and/or malolactic fermentation. Sulfur dioxide is
Cantoral Fernández, Jesús Manuel +4 more
core +2 more sources
Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor. [PDF]
, 2018 ATP-powered viral packaging motors are among the most powerful biomotors known. Motor subunits arranged in a ring repeatedly grip and translocate the DNA to package viral genomes into capsids.
Alam, Istiaq +4 more
core +3 more sources
F1000Research, 2013 Genetic manipulation in enterohemorrhagic E. coli O157:H7 is currently restricted to recombineering, a method that utilizes the recombination system of bacteriophage lambda, to introduce gene replacements and base changes inter alia into the genome ...
Martin G Marinus, Anthony R Poteete
doaj +1 more source
Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages
Frontiers in Microbiology, 2021 Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages).
Ann-Katrin Llarena +4 more
doaj +1 more source
Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones [PDF]
, 2016 Our previous paper (Wilkinson et al, 2016) used high-resolution cryo-electron microscopy to solve the structure of the Escherichia coli RecBCD complex, which acts in both the repair of double-stranded DNA breaks and the degradation of bacteriophage DNA ...
Aedo +44 more
core +5 more sources
Canine hepacivirus NS3 serine protease can cleave the human adaptor proteins MAVS and TRIF. [PDF]
PLoS ONE, 2012 Canine hepacivirus (CHV) was recently identified in domestic dogs and horses. The finding that CHV is genetically the virus most closely related to hepatitis C virus (HCV) has raised the question of whether HCV might have evolved as the result of close ...
Mariona Parera +4 more
doaj +1 more source
An Optimal Lysis Time Maximizes Bacteriophage Fitness in Quasi-Continuous Culture
mBio, 2022 Optimality models have a checkered history in evolutionary biology. While optimality models have been successful in providing valuable insight into the evolution of a wide variety of biological traits, a common objection is that optimality models are ...
Sherin Kannoly +2 more
doaj +1 more source
Protein chainmail variants in dsDNA viruses. [PDF]
, 2015 First discovered in bacteriophage HK97, biological chainmail is a highly stable system formed by concatenated protein rings. Each subunit of the ring contains the HK97-like fold, which is characterized by its submarine-like shape with a 5-stranded β ...
Chiou, Joshua, Zhou, Z Hong
core +2 more sources
Roles of orf60a and orf61 in Development of Bacteriophages λ and Φ24B
Viruses, 2018 The exo-xis region of lambdoid bacteriophage genomes contains several established and potential genes that are evolutionarily conserved, but not essential for phage propagation under laboratory conditions.
Aleksandra Dydecka +7 more
doaj +1 more source