Results 41 to 50 of about 169,837 (200)
An Abstraction Theory for Qualitative Models of Biological Systems [PDF]
Electronic Proceedings in Theoretical Computer Science, 2010 Multi-valued network models are an important qualitative modelling approach used widely by the biological community. In this paper we consider developing an abstraction theory for multi-valued network models that allows the state space of a model to be ...
Richard Banks, L. Jason Steggles
doaj +1 more source
Stochastic cellular fate decision making by multiple infecting lambda phage. [PDF]
PLoS ONE, 2014 Bacteriophage lambda is a classic system for the study of cellular decision making. Both experiments and mathematical models have demonstrated the importance of viral concentration in the lysis-lysogeny decision outcome in lambda phage. However, a recent
Matthew L Robb, Vahid Shahrezaei
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Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Kinetics of inactivation of bacteria responsible for infections in hospitals using UV-LED
HeliyonControlling the microbial load in the environment is crucial to prevent the spread of organisms. The continuous spread of nosocomial infections in hospital facilities and the emergence of the coronavirus (COVID-19) highlighted the importance of ...
Beatriz Rito +3 more
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The lambda red proteins promote efficient recombination between diverged sequences: implications for bacteriophage genome mosaicism. [PDF]
PLoS Genetics, 2008 Genome mosaicism in temperate bacterial viruses (bacteriophages) is so great that it obscures their phylogeny at the genome level. However, the precise molecular processes underlying this mosaicism are unknown.
Jann T Martinsohn +2 more
doaj +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Advanced Materials, EarlyView.Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Advanced Science, EarlyView.When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Can painting human cells with exogenous maltoporin enable efficient therapeutic gene transfer by bacteriophage lambda vectors? [PDF]
, 2009 Many gene therapy strategies require transfer of high-molecular weight DNA into human cells. To enable clinical trials, these vectors need to be produced on a large scale and at low cost.
Tolmachov, O +2 more
core +1 more source
Involvement of Escherichia coli DNA Replication Proteins in Phage Lambda Red-Mediated Homologous Recombination. [PDF]
PLoS ONE, 2013 The Red recombination system of bacteriophage lambda is widely used for genetic engineering because of its ability to promote recombination between bacterial chromosomes or plasmids and linear DNA species introduced by electroporation.
Anthony R Poteete
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Ultraviolet Reactivation in Bacteriophage Lambda
Journal of General Virology, 1970 Summary Reactivation of damaged phage λ v by recombination with prophage (prophage reactivation) and by u.v. irradiation of host bacteria (u.v. reactivation) were similar in that u.v.- and nitrous acid-damaged phage was reactivated in both, both were eliminated by three rec alleles, neither was much affected by hcr alleles, and both were dependent on ...
M G, Hart, J, Ellison
openaire +2 more sources