Results 121 to 130 of about 48,920 (278)

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Isolation and characterization bacteriophage for vibriosis therapy in fish [PDF]

, 2016
"Bacterial infections in aquaculture are commonly treated using antibiotics. However, due to health concern and environmental issues, new control strategies for bacterial diseases are needed.
Mohammad Tamrin Mohamad Lal
core  

Toward Modern Inhalational Bacteriophage Therapy: Nebulization of Bacteriophages of Burkholderia cepacia Complex

, 2008
Antibiotic-resistant bacterial infections have renewed interest in finding substitute methods of treatment. The purpose of the present in vitro study was to investigate the possibility of respiratory delivery of a Burkholderia cepacia complex (BCC ...
Golshani, Laleh, Dennis, Jonathan J., Finlay, Warren H., Seed, Kimberley D.   +3 more
core   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Bacteriophage therapy and infective endocarditis – is it realistic?

APMIS
Infective endocarditis (IE) is a severe infection of the inner heart. Even with current standard treatment, the mean in‐hospital mortality is as high as 15–20%, and 1‐year mortality is up to 40% for left‐sided IE. Importantly, IE mortality rates have not changed substantially over the past 30 years, and the incidence of IE is rising.
Emilie C. Pedersen, Christian Johann Lerche, Franziska Angelica Schwartz, Oana Ciofu, Joana Azeredo, Kim Thomsen, Claus Moser   +6 more
openaire   +4 more sources

Isolation and characterization of bacteriophage for vibriosis therapy in fish [PDF]

, 2016
Bacterial infections in aquaculture are commonly treated using antibiotics. However, due to health concern and environmental issues, new control strategies for bacterial diseases are needed. Therefore, this study was conducted to isolate and characterize
Mohammad Tamrin Mohamad Lal
core  

The Potential Use of Bacteriophage Therapy as a Treatment Option in a Post-Antibiotic Era

, 2016
The impending postantibiotic era creates an urgent requirement for alternative treatments of infectious diseases in humans and animals. Bacteriophages are viruses that infect and kill bacteria.
W.A. van der Westhuizen, Bragg, Robert Richard, Meyburgh, L., J.-Y. Lee, R.R. Bragg, Boucher, Charlotte Enastacia, E. Coetsee, C. Theron, van der Westhuizen, W. A., L. Meyburgh, C.E. Boucher, Lee, Ji-yun, Coetsee, Elke, Theron, Chrispian   +13 more
core   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source