Results 31 to 40 of about 44,922 (302)

The Presence of Bacteriophages in the Human Body: Good, Bad or Neutral?

Microorganisms, 2020
The presence of bacteriophages (phages) in the human body may impact bacterial microbiota and modulate immunity. The role of phages in human microbiome studies and diseases is poorly understood.
Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Maciej Żaczek, Jan Borysowski, Andrzej Górski   +4 more
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What Are the Potential Benefits of Using Bacteriophages in Periodontal Therapy?

Antibiotics, 2022
Periodontitis, which may result in tooth loss, constitutes both a serious medical and social problem. This pathology, if not treated, can contribute to the development of, among others, pancreatic cancer, cardiovascular diseases or Alzheimer’s disease ...
Jan Kowalski, Renata Górska, Martyna Cieślik, Andrzej Górski, Ewa Jończyk-Matysiak   +4 more
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Phage Therapy in Poland – a Centennial Journey to the First Ethically Approved Treatment Facility in Europe

Frontiers in Microbiology, 2020
Although phage discovery is an unquestionable merit of the English bacteriologist Frederick W. Twort and the Canadian–French microbiologist Félix d’Hérelle, who both discovered phages over 100 years ago, the Polish history of phage studies also dates ...
Maciej Żaczek, Beata Weber-Dąbrowska, Beata Weber-Dąbrowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Marzanna Łusiak-Szelachowska, Andrzej Górski, Andrzej Górski   +8 more
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Taking Bacteriophage Therapy Seriously: A Moral Argument [PDF]

BioMed Research International, 2014
The excessive and improper use of antibiotics has led to an increasing incidence of bacterial resistance. In Europe the yearly number of infections caused by multidrug resistant bacteria is more than 400.000, each year resulting in 25.000 attributable deaths. Few new antibiotics are in the pipeline of the pharmaceutical industry.
Gilbert Verbeken, Isabelle Huys, Jean-Paul Pirnay, Serge Jennes, Nina Chanishvili, Jacques Scheres, Andrzej Górski, Daniel De Vos, Carl Ceulemans   +8 more
openaire   +4 more sources

Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics

Viruses, 2017
Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes—contained in granules—that are potentially toxic ...
Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska, Barbara Owczarek, Ryszard Międzybrodzki, Marzanna Łusiak-Szelachowska, Norbert Łodej, Andrzej Górski   +6 more
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The Effect of Bacteriophage Preparations on Intracellular Killing of Bacteria by Phagocytes

Journal of Immunology Research, 2015
Intracellular killing of bacteria is one of the fundamental mechanisms against invading pathogens. Impaired intracellular killing of bacteria by phagocytes may be the reason of chronic infections and may be caused by antibiotics or substances that can be
Ewa Jończyk-Matysiak, Marzanna Łusiak-Szelachowska, Marlena Kłak, Barbara Bubak, Ryszard Międzybrodzki, Beata Weber-Dąbrowska, Maciej Żaczek, Wojciech Fortuna, Paweł Rogóż, Sławomir Letkiewicz, Krzysztof Szufnarowski, Andrzej Górski   +11 more
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The Appearance of Antiphage Antibodies in Sera of Patients Treated with Phages

Antibiotics
Background: Bacteriophages are neutralized by the sera of patients undergoing phage therapy (PT), particularly during local or concomitant local and oral phage administration in bone infections, soft tissue infections, or upper respiratory tract ...
Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Maciej Żaczek, Ryszard Międzybrodzki, Andrzej Górski   +4 more
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Isolation and Characterization of Phages Active against Paenibacillus larvae Causing American Foulbrood in Honeybees in Poland

Viruses, 2021
The aim of this study was the isolation and characterization, including the phage effect on honeybees in laboratory conditions, of phages active against Paenibacillus larvae, the causative agent of American Foulbrood—a highly infective and easily ...
Ewa Jończyk-Matysiak, Barbara Owczarek, Ewa Popiela, Kinga Świtała-Jeleń, Paweł Migdał, Martyna Cieślik, Norbert Łodej, Dominika Kula, Joanna Neuberg, Katarzyna Hodyra-Stefaniak, Marta Kaszowska, Filip Orwat, Natalia Bagińska, Anna Mucha, Agnieszka Belter, Mirosława Skupińska, Barbara Bubak, Wojciech Fortuna, Sławomir Letkiewicz, Paweł Chorbiński, Beata Weber-Dąbrowska, Adam Roman, Andrzej Górski   +22 more
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Bacteriophage-Mediated Cancer Gene Therapy

International Journal of Molecular Sciences, 2022
Bacteriophages have long been considered only as infectious agents that affect bacterial hosts. However, recent studies provide compelling evidence that these viruses are able to successfully interact with eukaryotic cells at the levels of the binding, entry and expression of their own genes.
Gleb Petrov, Maya Dymova, Vladimir Richter   +2 more
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Bacteriophage therapy

Microbiology Australia, 2013
Bacteriophages (phages) are viruses that infect only bacteria. They exhibit one of two types of life cycle; lytic (virulent) or lysogenic (temperate). They are non-toxic to other organisms, infecting, and in the case of lytic phages, multiplying rapidly within the bacterial host, ultimately killing it¹.
openaire   +3 more sources