Results 21 to 30 of about 188,039 (353)

Performance of Choline Geranate Deep Eutectic Solvent as Transdermal Permeation Enhancer: An In Vitro Skin Histological Study

Pharmaceutics, 2021
In the present research work, we addressed the changes in skin by which deep eutectic solvents (DES) enhanced transdermal permeation of bioactive compounds and propose a rationale for this mechanism. Several studies showed that these unusual liquids were
Rodrigo Boscariol, Érika A. Caetano, Erica C. Silva, Thais J. Oliveira, Raquel M. Rosa-Castro, Marta M. D. C. Vila, Victor M. Balcão   +6 more
doaj   +1 more source

Transdermal Permeation Assays of Curcumin Aided by CAGE-IL: In Vivo Control of Psoriasis

Pharmaceutics, 2022
Psoriasis is a clinically heterogeneous skin disease with an important genetic component, whose pathophysiology is not yet fully understood and for which there is still no cure.
Rodrigo Boscariol, Érika A. Caetano, Denise Grotto, Raquel M. Rosa-Castro, José M. Oliveira Junior, Marta M. D. C. Vila, Victor M. Balcão   +6 more
doaj   +1 more source

Phage Therapy Experience at the Eliava Phage Therapy Center: Three Cases of Bacterial Persistence

Viruses, 2021
In this retrospective descriptive study we focus on cases of three patients who underwent phage therapy procedures at Eliava Phage Therapy Center (EPTC) in Tbilisi, Georgia. Patients with chronic infectious diseases related to Pseudomonas aeruginosa (two
Elisabed Zaldastanishvili, Lika Leshkasheli, Mariam Dadiani, Lia Nadareishvili, Lia Askilashvili, Nino Kvatadze, Marina Goderdzishvili, Mzia Kutateladze, Nana Balarjishvili   +8 more
doaj   +1 more source

Isolation and Molecular Characterization of Two Novel Lytic Bacteriophages for the Biocontrol of Escherichia coli in Uterine Infections: In Vitro and Ex Vivo Preliminary Studies in Veterinary Medicine

Pharmaceutics, 2022
E. coli is one of the etiological agents responsible for pyometra in female dogs, with conventional treatment involving ovariohysterectomy. Here, we report the isolation and full characterization of two novel lytic phages, viz.
Victor M. Balcão, Bianca G. Belline, Erica C. Silva, Pablo F. F. B. Almeida, Denicezar Â. Baldo, Lara R. P. Amorim, José M. Oliveira Júnior, Marta M. D. C. Vila, Fernando S. Del Fiol   +8 more
doaj   +1 more source

Bacteriophages and the Immune System.

Annual Review of Virology, 2021
Bacteriophages-viruses that infect bacteria-are abundant within our bodies, but their significance to human health is only beginning to be explored.
M. Popescu, Jonas D. Van Belleghem, A. Khosravi, P. Bollyky   +3 more
semanticscholar   +1 more source

Phenotypic and Genetic Characterization of Aeromonas hydrophila Phage AhMtk13a and Evaluation of Its Therapeutic Potential on Simulated Aeromonas Infection in Danio rerio

Viruses, 2022
Phage therapy can be an effective alternative to standard antimicrobial chemotherapy for control of Aeromonas hydrophila infections in aquaculture. Aeromonas hydrophila-specific phages AhMtk13a and AhMtk13b were studied for basic biological properties ...
Nino Janelidze, Ekaterine Jaiani, Elene Didebulidze, Ia Kusradze, Adam Kotorashvili, Kristine Chalidze, Ketevan Porchkhidze, Tinatin Khukhunashvili, George Tsertsvadze, Dodo Jgenti, Tamaz Bajashvili, Marina Tediashvili   +11 more
doaj   +1 more source

Interactions of Bacteriophages with Animal and Human Organisms—Safety Issues in the Light of Phage Therapy

International Journal of Molecular Sciences, 2021
Bacteriophages are viruses infecting bacterial cells. Since there is a lack of specific receptors for bacteriophages on eukaryotic cells, these viruses were for a long time considered to be neutral to animals and humans.
M. Podlacha, Łukasz Grabowski, Katarzyna Kosznik-Kawśnicka, Karolina Zdrojewska, Małgorzata Stasiłojć, G. Węgrzyn, A. Węgrzyn   +6 more
semanticscholar   +1 more source

Bacteriophage-Based Biosensing of Pseudomonas aeruginosa: An Integrated Approach for the Putative Real-Time Detection of Multi-Drug-Resistant Strains

Biosensors, 2021
During the last decennium, it has become widely accepted that ubiquitous bacterial viruses, or bacteriophages, exert enormous influences on our planet’s biosphere, killing between 4–50% of the daily produced bacteria and constituting the largest genetic ...
Liliam K. Harada, Waldemar Bonventi Júnior, Erica C. Silva, Thais J. Oliveira, Fernanda C. Moreli, José M. Oliveira Júnior, Matthieu Tubino, Marta M. D. C. Vila, Victor M. Balcão   +8 more
doaj   +1 more source

Characterization of four virulent Klebsiella pneumoniae bacteriophages, and evaluation of their potential use in complex phage preparation

Virology Journal, 2021
Background Nowadays, hundreds of thousands of deaths per year are caused by antibiotic resistant nosocomial infections and the prognosis for future years is much worse, as evidenced by modern research. Bacteria of the Klebsiella genus are one of the main
F. Zurabov, E. Zhilenkov
semanticscholar   +1 more source

New Bacteriophages with Podoviridal Morphotypes Active against Yersinia pestis: Characterization and Application Potential

Viruses, 2023
Phages of highly pathogenic bacteria represent an area of growing interest for bacterial detection and identification and subspecies typing, as well as for phage therapy and environmental decontamination. Eight new phages—YpEc56, YpEc56D, YpEc57, YpEe58,
Tamar Suladze, Ekaterine Jaiani, Marina Darsavelidze, Maia Elizbarashvili, Olivier Gorge, Ia Kusradze, Tamar Kokashvili, Nino Lashkhi, George Tsertsvadze, Nino Janelidze, Svetlana Chubinidze, Marina Grdzelidze, Shota Tsanava, Eric Valade, Marina Tediashvili   +14 more
doaj   +1 more source