Results 61 to 70 of about 10,209 (169)

Introduction of the Bacteroides ruminicola xylanase gene into the Bacteroides thetaiotaomicron chromosome for production of xylanase activity [PDF]

Applied and Environmental Microbiology, 1991
The xylanase gene from the ruminal bacterium Bacteroides ruminicola 23 is highly expressed in colonic Bacteroides species when carried on plasmid pVAL-RX. In order to stabilize xylanase expression in the absence of antibiotic selection, the xylanase gene was introduced into the chromosome of Bacteroides thetaiotaomicron 5482 by using suicide vector ...
T R, Whitehead, M A, Cotta, R B, Hespell
openaire   +2 more sources

Bacterial sialidases subvert the complement system through desialylation

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Bacterial sialidases (neuraminidases) are widely studied virulence factors, yet their impact on the complement system, a central component of innate immunity, remains poorly understood. Here, we investigate the effects of six sialidases from five human pathogens, including Bacteroides fragilis, Clostridium perfringens, Tannerella forsythia ...
Kurni Kurniyati, Nicholas D. Clark, Qin Fu, Sheng Zhang, Weigang Qiu, Michael G. Malkowski, Chunhao Li   +6 more
wiley   +1 more source

Developing a Bacteroides System for Function-Based Screening of DNA from the Human Gut Microbiome

mSystems, 2018
Functional metagenomics is a powerful method that allows the isolation of genes whose role may not have been predicted from DNA sequence. In this approach, first, environmental DNA is cloned to generate metagenomic libraries that are maintained in ...
Kathy N. Lam, Eric C. Martens, Trevor C. Charles   +2 more
doaj   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, Volume 13, Issue 57, 14 October 2026.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Colonial variation, capsule formation, and bacteriophage resistance in Bacteroides thetaiotaomicron [PDF]

Applied and Environmental Microbiology, 1978
A Bacteroides thetaiotaomicron strain segregated two unstable colonial variants at high frequency. There is a correlation between colony morphology, encapsulation, Giemsa staining, and bacteriophage resistance.
S, Burt, S, Meldrum, D R, Woods, D T, Jones   +3 more
openaire   +2 more sources

Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides

Nature Communications, 2020
Human gut bacteria depolymerize glycans into their sugar components, which otherwise cannot be processed by their host. Here, the authors characterise the endo-β-N-acetylglucosaminidase EndoBT-3987 from the Gram-negative symbiont Bacteroides ...
Beatriz Trastoy, Jonathan J. Du, Erik H. Klontz, Chao Li, Javier O. Cifuente, Lai-Xi Wang, Eric J. Sundberg, Marcelo E. Guerin   +7 more
doaj   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Distinct effects of different Bacteroides strains on depressive-like behavior via a gut-Th1/Th17 cells-brain axis

Communications Biology
Extensive evidence links gut microbiota to the pathogenesis of major depressive disorder (MDD), yet the specific microbial species involved remain unclear. Here, we identify distinct roles of three Bacteroides species—B. uniformis, B.
Zhiyu Li, Peilin Qin, Zuoli Sun, Liangkang Li, Peng Liang, Yimei Zhao, Siyu Ren, Gang Wang, Jian Yang   +8 more
doaj   +1 more source

Crystal structure of dipeptidyl peptidase III from the human gut symbiont Bacteroides thetaiotaomicron. [PDF]

PLoS ONE, 2017
Bacteroides thetaiotaomicron is a dominant member of the human intestinal microbiome. The genome of this anaerobe encodes more than 100 proteolytic enzymes, the majority of which have not been characterized.
Igor Sabljić, Nevenka Meštrović, Bojana Vukelić, Peter Macheroux, Karl Gruber, Marija Luić, Marija Abramić   +6 more
doaj   +1 more source

Cross‐Sectional Associations Between Gut Microbiota and Neuroimaging Changes in Post‐COVID‐19 Condition

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
In patients with post‐COVID‐19 condition, a significant shift in gut microbiota composition can be observed, marked by a decrease in butyrate‐producing taxa. Relevant taxa correlate with clinical symptoms, structural and functional brain changes, which suggests potential therapeutic targets and highlight the need for further investigation in their ...
Sophie Wetz, Ravi Dadsena, Nicole Treichel, Ana S. Costa, Anna Hofmann, Sandro Romanzetti, Thomas Clavel, Kathrin Reetz, Julia Walders   +8 more
wiley   +1 more source