Results 81 to 90 of about 9,722 (166)

Amino acid homeostasis in the kidney: Physiological roles and pathological dysregulation

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Amino acids are fundamental to life as protein building blocks and key regulators of metabolism and signaling. The kidney plays a critical, yet underappreciated, role in amino acid homeostasis through three interconnected pillars: selective glomerular filtration, efficient tubular reabsorption, and metabolic processing, which includes de novo ...
Shuo Liu, Caifeng Shi, Yang Zhou, Chunsun Dai   +3 more
wiley   +1 more source

Metabolite dependence of antibiotic susceptibility in a gut microbe

mSphere
Antibiotics save lives but can have unwanted effects on our gut microbes, thereby contributing to disease. A mechanistic understanding of how such microbes respond to antibiotics is hence critical. Recently in mSphere, Nilson et al.
Kyle R. Allison
doaj   +1 more source

The First Metronidazole-Resistant Bacteroides Species Isolated at Marmara University Hospital: Bacteroides thetaiotaomicron

Mikrobiyoloji Bulteni, 2013
Bacteroides species, the predominant constituents of the human intestinal microbiota can cause serious intraabdominal and postoperative wound infections and bacteremia. Moreover, these bacteria are more resistant to antimicrobial agents than the other anaerobes.
Nurver, Toprak Ülger, Elvan, Sayın, Ad, Soyad, Faysal, Dane, Güner, Söyletir   +4 more
openaire   +2 more sources

Unveiling the causal effects of gut microbiome on trimethylamine N-oxide: evidence from Mendelian randomization

Frontiers in Microbiology
ObjectiveThe relationship between gut microbiome and trimethylamine oxide (TMAO) has not been fully elucidated. We aimed to assess the causal effects of different gut microbes on TMAO using Mendelian randomization (MR).MethodsGut microbiome and TMAO ...
Yunfeng Yu, Yunfeng Yu, Yuman Yin, Juan Deng, Xinyu Yang, Siyang Bai, Rong Yu, Rong Yu   +7 more
doaj   +1 more source

Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium

Cell Reports
Summary: Isogenic bacteria can be phenotypically diverse. This heterogeneity is evident in the Bacteroidota, a predominant phylum of the human gut microbiota.
Elise Bornet, Gianluca Prezza, Laura Cecchino, Laura Jenniches, Jochen Behrends, Caroline Tawk, Kerwyn Casey Huang, Till Strowig, Jörg Vogel, Lars Barquist, Antoine-Emmanuel Saliba, Alexander J. Westermann   +11 more
doaj   +1 more source

Mannose Foraging by Bacteroides thetaiotaomicron [PDF]

Journal of Biological Chemistry, 2007
Louise E. Tailford, Victoria A. Money, Nicola L. Smith, Claire Dumon, Gideon J. Davies, Harry J. Gilbert   +5 more
openaire   +1 more source

Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages

Gut Microbes
Bacteriophages (phages) and bacteria within the gut microbiome persist in long-term stable coexistence. These interactions are driven by eco-evolutionary dynamics, where bacteria employ a variety of mechanisms to evade phage infection, while phages rely ...
Adrián Cortés-Martín, Colin Buttimer, Jessie L. Maier, Ciara A. Tobin, Lorraine A. Draper, R. Paul Ross, Manuel Kleiner, Colin Hill, Andrey N. Shkoporov   +8 more
doaj   +1 more source

Bacterial constipation: Mucin-degrading intestinal commensal bacteria cause constipation

Gut Microbes
The contribution of gut microbes to constipation remains mechanistically underexplored, despite constipation being one of the most prevalent gastrointestinal disorders.
Tomonari Hamaguchi, Noriaki Gibo, Misuzu Ohara, Mikako Ito, Tomoyuki Ogura, Jun-Ichi Takeda, Hiroshi Nishiwaki, Fei Zhao, Ryo Kinoshita-Daitoku, Masashi Hattori, Koji Nonogaki, Tetsuya Maeda, Kenichi Kashihara, Yoshio Tsuboi, Masaaki Hirayama, Mitsuhiro Fujishiro, Hiroki Kawashima, Kinji Ohno   +17 more
doaj   +1 more source

Differential toll-like receptor 2 activation by Akkermansia muciniphila and Bacteroides thetaiotaomicron mediates the beneficial effects of Fu brick tea polysaccharide against colitis

Pharmacological Research
Fu Brick Tea Polysaccharide (FBTP) ameliorates dextran sulfate sodium (DSS)-induced colitis in mice. However, the key intestinal bacterial strains and downstream molecular mechanisms mediating these protective effects remain unclear.
Gaolong Zuo, Feifei Chang, Xinyi Yuan, Yujie Shen, Xiaoli Guo, Bo Tang, Jian-an Huang, Zhonghua Liu, Yong Lin   +8 more
doaj   +1 more source

Structure-dependent degradation of milk oligosaccharides by newly isolated intestinal commensal bacterial strains from suckling piglets and rabbits

BMC Microbiology
Background Mammalian milk oligosaccharides serve as the first natural prebiotics for newborns, promoting the development of a beneficial gut microbiota. The ability of bacteria to use these complex sugars depends on their structure, but data are limited ...
Mathilde Rumeau, Sead Chadi, Frederic Pepke, Martin Beaumont, Cláudia M. Vicente, Agathe Juppeau, Céline Vandecasteele, Laurent Cauquil, Géraldine Pascal, Philippe Langella, Christelle Knudsen, Sylvie Combes, Rebeca Martín   +12 more
doaj   +1 more source