Results 11 to 20 of about 33,886 (209)

Chromatin Remodeling BAF (SWI/SNF) Complexes in Neural Development and Disorders [PDF]

Frontiers in Molecular Neuroscience, 2017
The ATP-dependent BRG1/BRM associated factor (BAF) chromatin remodeling complexes are crucial in regulating gene expression by controlling chromatin dynamics.
Godwin Sokpor, Yuanbin Xie, Joachim Rosenbusch, Tran Tuoc, Tran Tuoc   +4 more
doaj   +4 more sources

The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma. [PDF]

Mol Cell, 2022
Zullow HJ, Sankar A, Ingram DR, Samé Guerra DD, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J, Lazar AJ, Kadoch C.   +11 more
europepmc   +2 more sources

Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML. [PDF]

Mol Cell, 2021
Riedel SS, Lu C, Xie HM, Nestler K, Vermunt MW, Lenard A, Bennett L, Speck NA, Hanamura I, Lessard JA, Blobel GA, Garcia BA, Bernt KM.   +12 more
europepmc   +2 more sources

A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms. [PDF]

Cell, 2020
Mashtalir N, Suzuki H, Farrell DP, Sankar A, Luo J, Filipovski M, D'Avino AR, St Pierre R, Valencia AM, Onikubo T, Roeder RG, Han Y, He Y, Ranish JA, DiMaio F, Walz T, Kadoch C.   +16 more
europepmc   +2 more sources

The role of the polybromo-associated BAF complex in development. [PDF]

Biochem Cell Biol
Chromatin is dynamically regulated during development, where structural changes affect the transcription of genes required to promote different cell types. One of the chromatin regulatory factors responsible for transcriptional regulation during development is the SWItch/Sucrose Non-Fermentable (SWI/SNF) complex, an ATP-dependent chromatin remodeling ...
Park J, Kirkland JG.
europepmc   +3 more sources

Long non-coding RNA uc.291 controls epithelial differentiation by interfering with the ACTL6A/BAF complex. [PDF]

EMBO Rep, 2020
Panatta E, Lena AM, Mancini M, Smirnov A, Marini A, Delli Ponti R, Botta-Orfila T, Tartaglia GG, Mauriello A, Zhang X, Calin GA, Melino G, Candi E.   +12 more
europepmc   +2 more sources

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma. [PDF]

Cancer Discov, 2022
Abstract Diffuse midline gliomas are uniformly fatal pediatric central nervous system cancers that are refractory to standard-of-care therapeutic modalities. The primary genetic drivers are a set of recurrent amino acid substitutions in genes encoding histone H3 (H3K27M), which are currently ...
Panditharatna E, Marques JG, Wang T, Trissal MC, Liu I, Jiang L, Beck A, Groves A, Dharia NV, Li D, Hoffman SE, Kugener G, Shaw ML, Mire HM, Hack OA, Dempster JM, Lareau C, Dai L, Sigua LH, Quezada MA, Stanton AJ, Wyatt M, Kalani Z, Goodale A, Vazquez F, Piccioni F, Doench JG, Root DE, Anastas JN, Jones KL, Conway AS, Stopka S, Regan MS, Liang Y, Seo HS, Song K, Bashyal P, Jerome WP, Mathewson ND, Dhe-Paganon S, Suvà ML, Carcaboso AM, Lavarino C, Mora J, Nguyen QD, Ligon KL, Shi Y, Agnihotri S, Agar NYR, Stegmaier K, Stiles CD, Monje M, Golub TR, Qi J, Filbin MG.   +54 more
europepmc   +4 more sources

Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development. [PDF]

Int J Mol Sci, 2019
El Hadidy N, Uversky VN.
europepmc   +2 more sources

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma. [PDF]

Cancer Cell, 2018
McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM, Araujo DM, Wang WL, Tsai JW, Yeagley M, Wagner AJ, Futreal PA, Khan J, Lazar AJ, Kadoch C.   +18 more
europepmc   +2 more sources

Critical role of the BAF chromatin remodeling complex during murine neural crest development.

PLoS Genetics, 2021
The BAF complex plays an important role in the development of a wide range of tissues by modulating gene expression programs at the chromatin level. However, its role in neural crest development has remained unclear.
Kathleen Wung Bi-Lin, Pratap Veerabrahma Seshachalam, Tran Tuoc, Anastassia Stoykova, Sujoy Ghosh, Manvendra K Singh   +5 more
doaj   +1 more source