Results 91 to 100 of about 20,980 (270)

The protective effects of baicalin for respiratory diseases: an update and future perspectives

Frontiers in Pharmacology, 2023
Background: Respiratory diseases are common and frequent diseases. Due to the high pathogenicity and side effects of respiratory diseases, the discovery of new strategies for drug treatment is a hot area of research.
Siyu Song, Lucky Ding, Guang-ping Liu, Tian Chen, Meiru Zhao, Xueyan Li, Min Li, Hongyu Qi, Jinjin Chen, Ziyuan Wang, Ying Wang, Jing Ma, Qi Wang, Xiangyan Li, Zeyu Wang   +14 more
semanticscholar   +1 more source

Baicalin as a Regulator of Peroxisome Proliferator‐Activated Receptor Gamma: Alleviating Sepsis‐Induced Liver Injury by Inhibiting the Cluster of Differentiation 14/Nuclear Factor Kappa B Signaling Pathway

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Baicalin (BA) alleviates sepsis‐induced liver injury through activating peroxisome proliferator‐activated receptor gamma (PPARγ) and inhibiting the Cluster of Differentiation 14 (CD14)/Nuclear Factor kappa B (NF‐κB) pathway. ABSTRACT Background Sepsis frequently results in multiple organ failure, with the liver particularly susceptible to sepsis ...
Hui Wang, Mengmeng Guo, Xueling Zeng, Yuqi Hu, Jiawei Ma, Yufei Chang   +5 more
wiley   +1 more source

The effects of baicalin on piglets challenged with Glaesserella parasuis

Veterinary Research, 2020
Glaesserella parasuis (G. parasuis) causes porcine vascular inflammation and damage. Baicalin is reported to have antioxidant and anti-inflammatory functions. However, whether baicalin protects piglets against G.
Shulin Fu, Ronghua Yin, Sanling Zuo, Jun Liu, Yunfei Zhang, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Zhongyuan Wu, Yongqing Hou, Chien-An Andy Hu   +11 more
doaj   +1 more source

Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma [PDF]

, 2015
ETHNOPHARMACOLOGICAL RELEVANCE: An oriental medicinal formulation, Huanglian Jiedu Decoction (HLJDD), has been well documented in few Traditional Chinese Medicine Classics 1300 years ago for treatment of heat and dampness-related diseases.
Cheung, F, Feng, Y, Hong, M, Lao, L, Nagamatsu, T, Tan, HY, Wang, N   +6 more
core   +1 more source

Baicalin and Baicalein Enhance Cytotoxicity, Proapoptotic Activity, and Genotoxicity of Doxorubicin and Docetaxel in MCF-7 Breast Cancer Cells

Molecules
Breast cancer is a major health concern and the leading cause of death among women worldwide. Standard treatment often involves surgery, radiotherapy, and chemotherapy, but these come with side effects and limitations.
Joanna Bernasińska-Słomczewska, Pawel Hikisz, A. Pieniazek, A. Koceva-Chyła   +3 more
semanticscholar   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer [PDF]

Pharmacia
Background: Breast cancer is one of the primary causes of death in women worldwide. Yearly, a quarter of cancer cases in women are breast cancer. The problem is aggravated by the emergence of chemotherapeutic resistance.
Dima Awajan, Anas H. A. Abu-Humaidan, Wamidh H. Talib   +2 more
doaj   +3 more sources

Two CYP82D Enzymes Function as Flavone Hydroxylases in the Biosynthesis of Root-Specific 4′-Deoxyflavones in Scutellaria baicalensis [PDF]

, 2018
Baicalein, wogonin, and their glycosides are major bioactive compounds found in the medicinal plant Scutellaria baicalensis Georgi. These flavones can induce apoptosis in a variety of cancer cell lines but have no effect on normal cells.
Chen, Xiao-Ya, Cui, Meng-Ying, Hill, Lionel, Hu, Yonghong, Levsh, Olesya, Li, Jie, Liu, Jie, Martin, Cathie, Weng, Jing-Ke, Yang, Dongfeng, Yang, Lei, Zhao, Qing   +11 more
core   +1 more source

Research Progress of Ferroptosis in Cerebral Infarction

Brain and Behavior, Volume 16, Issue 1, January 2026.
Cerebral infarction triggers ischemia–reperfusion injury, leading to iron overload, oxidative stress, and mitochondrial dysfunction, which together initiate ferroptosis—an iron‐dependent, lipid peroxidation–driven form of neuronal death. Disruption of the System Xc−/GSH/GPX4 antioxidant axis and ACSL4‐mediated PUFA phospholipid enrichment accelerates ...
Yilan Fei, Qi Leng
wiley   +1 more source

The Evaluation of the Body Weight Lowering Effects of Herbal Extract THI on Exercising Healthy Overweight Humans: A Randomized Double-Blind, Placebo-Controlled Trial [PDF]

, 2013
We investigated the effects of herbal extracts, a mixture of Scutellariae Radix and Platycodi Radix containing the active ingredients Baicalin and Saponin (target herbal ingredient (THI)), on lowering body weight.
Soo Hyun Cho, Yoosik Yoon, Young Yang
core   +1 more source