Results 81 to 90 of about 20,980 (270)

The protective effect of baicalin against cyclophosphamideinduced testicular damage in rats

Open Veterinary Journal
Background: Cyclophosphamide (CTX) is a widely used chemotherapeutic agent; however, its clinical application is often limited by significant reproductive toxicity, particularly testicular damage.
Jianqin Li, Chunlian Song, Xue Zhang, Yalong Sun, Nan Wang, Xianghua Shu   +5 more
doaj   +1 more source

Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway

Journal of Neuroinflammation, 2019
Background Baicalin, which is isolated from Radix Scutellariae, possesses strong biological activities including an anti-inflammation property. Recent studies have shown that the anti-inflammatory effect of baicalin is linked to toll-like receptor 4 ...
Li-Ting Guo, Si-Qi Wang, Jing Su, Li-Xing Xu, Zhou-Ye Ji, Ru-Yi Zhang, Qin-Wen Zhao, Zhan-Qiang Ma, Xue-Yang Deng, Shi-Ping Ma   +9 more
doaj   +1 more source

Study of Baicalin toward COVID-19 Treatment: In silico Target Analysis and in vitro Inhibitory Effects on SARS-CoV-2 Proteases

Biomedicine Hub, 2021
Negative impacts of COVID-19 on human health and economic and social activities urge scientists to develop effective treatments. Baicalin is a natural flavonoid, extracted from a traditional medicinal plant, previously reported with anti-inflammatory ...
Chingju Lin, Fuu-Jen Tsai, Yuan-Man Hsu, Tsung-Jung Ho, Guo-Kai Wang, Yu-Jen Chiu, Hai-Anh Ha, Jai-Sing Yang   +7 more
doaj   +1 more source

Dissolution and pharmacokinetics of baicalin–polyvinylpyrrolidone coprecipitate

Journal of Pharmacy and Pharmacology, 2013
Abstract Objectives Baicalin–polyvinylpyrrolidone coprecipitate was prepared with the aim of improving the dissolution and bioavailability of the baicalin. Methods The dissolution of the coprecipitate in capsule form was tested and ...
Bibo, Li, Mei, He, Wei, Li, Zhibin, Luo, Ying, Guo, Yajun, Li, Chunbao, Zang, Bo, Wang, Fang, Li, Shaolin, Li, Ping, Ji   +10 more
openaire   +2 more sources

Hesperetin Mitigate Idiopathic Pulmonary Fibrosis by Regulating Gut Microbiota and Acetate and Butyrate Levels via the Gut‐Lung Axis

Food Frontiers, Volume 7, Issue 2, March 2026.
Hesperetin inhibits bleomycin‐induced idiopathic pulmonary fibrosis by regulating gut microbiota and acetate and butyrate levels via the gut‐lung axis. ABSTRACT In the post‐epidemic and aging era, idiopathic pulmonary fibrosis (IPF) has become one of the major diseases endangering human health.
Xia Meng, Zeren Cheng, Xianpu Huang, Mengqi Fu, Ling Shen, Kejing Tang, Shuxun Liu, Mingfei Yao, Qing Gu, Ping Li   +9 more
wiley   +1 more source

A fixed combination of probiotics and herbal extracts attenuates intestinal barrier dysfunction from inflammatory stress in an in vitro model using Caco-2 cells. [PDF]

, 2019
Background: Inflammatory Bowel Diseases (IBD), are considered a growing global disease, with about ten million people being affected worldwide. Maintenance of intestinal barrier integrity is crucial for preventing IBD onset and exacerbations. Some recent
Biagi, M, Borgonetti, V, Carnevali, I, Catanzaro, D, Cocetta, V, Giron, MC, Governa, P, Montopoli, M, Ragazzi, E   +8 more
core   +1 more source

Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF‐κB signalling pathway

Nephrology, 2023
Inflammation and apoptosis are main pathological processes that lead to the development of hyperuricemic nephropathy (HN). This study aims to explore whether baicalin (BA) and baicalein (BAI) can relieve the damage through PI3K/AKT/NF‐κB signal pathway ...
Ziyuan Liu, Huilong Xiang, Qin Deng, Wanting Fu, Yang Li, Zejun Yu, Yinsheng Qiu, Zhinan Mei, Lingyun Xu   +8 more
semanticscholar   +1 more source

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

Advanced Science, Volume 13, Issue 9, 13 February 2026.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

Protective effect and mechanism of baicalin on lung inflammatory injury in BALB/cJ mice induced by PM2.5

Ecotoxicology and Environmental Safety, 2022
The public health harms caused by fine particulate matter (PM2.5) have become a global focus, with PM2.5 exposure recognized as a critical risk factor for global morbidity and mortality.
Lili Deng, Mingyue Ma, Shuying Li, Lin Zhou, Sun Ye, Juan Wang, Qiaoqiao Yang, Chunling Xiao   +7 more
doaj   +1 more source

Baicalin Ameliorates Depression-like Behaviors via Inhibiting Neuroinflammation and Apoptosis in Mice

International Journal of Molecular Sciences
Depression is a common neuropsychiatric disease which brings an increasing burden to all countries globally. Baicalin, a flavonoid extracted from the dried roots of Scutellaria, has been reported to exert anti-inflammatory, antioxidant, and ...
Yuhang Yi, Guiyu Liu, Ye Li, Changmin Wang, Bin Zhang, Haiyan Lou, Shuyan Yu   +6 more
semanticscholar   +1 more source