Results 31 to 40 of about 1,736 (178)
Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae
Clinical and Translational Science, Volume 14, Issue 3, Page 791-805, May 2021., 2021 Abstract Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become pathogenic and cause severe cerebral infections, named granulomatous amoebic encephalitis (GAE ...
Alexandre Taravaud +3 more
wiley +1 more source
Balamuthia mandrillaris resistance to hostile conditions [PDF]
Journal of Medical Microbiology, 2008 The resistance of Balamuthia mandrillaris to physical, chemical and radiological conditions was tested. Following treatments, viability was determined by culturing amoebae on human brain microvascular endothelial cells for up to 12 days. B. mandrillaris cysts were resistant to repeated freeze–thawing (five times), temperatures of up to 70 °C, 0.5 % SDS,
Ortega Rivas, Antonio +2 more
openaire +3 more sources
Increasing Importance of Balamuthia mandrillaris [PDF]
Clinical Microbiology Reviews, 2008 SUMMARY Balamuthia mandrillaris is an emerging protozoan parasite, an agent of granulomatous amoebic encephalitis involving the central nervous system, with a case fatality rate of >98%. This review presents our current understanding of Balamuthia infections, their ...
Abdul, Matin +3 more
openaire +2 more sources
Brain-eating amoebae: Predilection sites in the brain and disease outcome [PDF]
, 2017 Acanthamoeba spp. and Balamuthia mandrillaris are causative agents of granulomatous amoebic encephalitis (GAE), while Naegleria fowleri causes primary amoebic meningoencephalitis (PAM).
Khan, Naveed Ahmed * +2 more
core +1 more source
Fatal Balamuthia mandrillaris brain infection associated with improper nasal lavage
International Journal of Infectious Diseases, 2018 We report the case of a 69-year-old female who presented with a chronic nasal skin rash, new onset focal seizure, and a cerebral ring-enhancing lesion after a year of improper nasal irrigation.
Keenan J. Piper +5 more
doaj +1 more source
Serum antibodies to Balamuthia mandrillaris, a free-living amoeba recently demonstrated to cause granulomatous amoebic encephalitis [PDF]
, 1999 © 1999 by the Infectious Diseases Society of America. All rights reserved.Free-living amoebae cause three well-defined disease entities: a rapidly fatal primary meningoencephalitis, a chronic granulomatous amoebic encephalitis (GAE), and a chronic ...
Carter, R., Ferrante, A., Huang, Z.
core +1 more source
Environmentally derived Balamuthia mandrillaris contains endosymbiotic bacteria. [PDF]
Parasitol ResBalamuthia mandrillaris is an environmentally derived, free-living amoeba that causes fatal meningoencephalitis. We previously isolated B. mandrillaris from soil in the Aomori Prefecture and attempted to culture the cell-free amoeba using liquid medium; however, this was difficult to achieve because of contamination of the medium with endogenous ...
Yamanouchi K +6 more
europepmc +2 more sources
A 76‐year‐old male with multiple enhancing brain lesions
, 2022 Brain Pathology, Volume 32, Issue 3, May 2022.
Kathryn L. Eschbacher +5 more
wiley +1 more source
Targeting brain-eating amoebae infections [PDF]
, 2017 Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous.
Khan, Naveed Ahmed * +2 more
core +1 more source
Balamuthia mandrillarisexhibits metalloprotease activities [PDF]
FEMS Immunology & Medical Microbiology, 2006 Balamuthia mandrillaris is a recently identified protozoan pathogen that can cause fatal granulomatous encephalitis. However, the pathogenesis and pathophysiology of B. mandrillaris encephalitis remain unclear. Because proteases may play a role in the central nervous system (CNS) pathology, we used spectrophotometric, cytopathic and zymographic assays ...
Abdul, Matin +3 more
openaire +2 more sources