Molecular Characterization of Microrna Interference and Aristolochic Acid Intoxication Found in Upper Tract Urothelial Carcinoma in Patients with Balkan Endemic Nephropathy: A Systematic Review of the Current Literature [PDF]
Balkan Journal of Medical Genetics, 2022 The term “aristolochic acid nephropathy” (AAN) is used to include any form of toxic interstitial nephropathy that is caused either by ingestion of plants containing aristolochic acids (AA) or by the environmental contaminants in food such as in Balkan ...
Bašić D +3 more
doaj +4 more sources
Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy [PDF]
Medicina, 2019 Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons.
Ljubica Djukanović +4 more
doaj +4 more sources
Association of SOD2 (rs4880) and GPX1 (rs1050450) Gene Polymorphisms with Risk of Balkan Endemic Nephropathy and its Related Tumors [PDF]
Medicina, 2019 Background and Objectives: Experimental data show that superoxide dismutase 2 (SOD2) is involved in ochratoxin (OTA)-induced nephrotoxicity, whereas clinical data indicate the role of SOD2 rs4880 or glutathione peroxidase 1 (GPX1) rs1050450 polymorphisms
Biljana Dragicevic +10 more
doaj +4 more sources
Urine Metabolomic Signature of People Diagnosed with Balkan Endemic Nephropathy and Other Types of Chronic Kidney Disease Compared with Healthy Subjects in Romania [PDF]
Metabolites, 2023 Metabolomic analysis methods were employed to determine biomarkers for various chronic kidney diseases (CKDs). Modern analytical methods were developed and applied successfully to find a specific metabolomic profile in urine samples from CKD and Balkan ...
Valentin L. Ordodi +6 more
doaj +4 more sources
Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN) [PDF]
BMC Medical Genetics, 2012 Background Balkan Endemic Nephropathy (BEN) is late-onset kidney disease thought to arise from chronic exposure to aristolochic acid, a phytotoxin that contaminates wheat supplies in rural areas of Eastern Europe.
Wooding Stephen P +5 more
doaj +4 more sources
Glomerular Filtration Rate in Examined Population of Bosnian Posavina - Region of Balkan Endemic Nephropathy [PDF]
Biomolecules & Biomedicine, 2010 Balkan endemic nephropathy (BEN) is chronic tubulointersticial nephritis of unknown aetiology characterized by an insidious onset and gradual progression to end stage renal disease (ESRD).
Mirna Alečković +5 more
doaj +4 more sources
Early Screening of Balkan Endemic Nephropathy. [PDF]
Mater Sociomed, 2017 Balkan endemic nephropathy (BEN) is a chronic irreversible interstitial sclerosis, for which over the last 25 years, chronic exposure to aristolochic acid from the contaminated cereal seeds has been considered the most likely cause. The aim of our research is to reevaluate trends of disease and to try to obtain new information about practical ...
Trnacevic S +3 more
europepmc +5 more sources
Unusual Urothelial Tumors and Refractory Uremia Due to Balkan Endemic Nephropathy: A Case Report [PDF]
Journal of Investigative Medicine High Impact Case ReportsBalkan endemic nephropathy (BEN) is a rare progressive chronic renal disease found in residents living along the Balkan peninsula. We present a 92-year-old female who complained initially of cardio-respiratory symptoms and was found to have an acute ...
Gevorg Arabyan BS +5 more
doaj +4 more sources
Values of Alpha 1 Microglobulin Does Not Differ between Individuals with and without Family History of Balkan Endemic Nephropathy [PDF]
International Journal of Nephrology, 2014 Aim. The aim of this study was to compare urinary alpha 1 microglobulin (A1MG) in healthy individuals with and without family burden for Balkan endemic nephropathy (BEN) in an endemic village. Methods. Otherwise healthy inhabitants with microalbuminuria
Mirna Aleckovic-Halilovic +7 more
doaj +4 more sources
Is Increased Susceptibility to Balkan Endemic Nephropathy in Carriers of Common GSTA1 (*A/*B) Polymorphism Linked with the Catalytic Role of GSTA1 in Ochratoxin A Biotransformation? Serbian Case Control Study and In Silico Analysis [PDF]
Toxins, 2014 Although recent data suggest aristolochic acid as a putative cause of Balkan endemic nephropathy (BEN), evidence also exists in favor of ochratoxin A (OTA) exposure as risk factor for the disease.
Zorica Reljic +9 more
doaj +4 more sources