Balkan Endemic Nephropathy: An Autopsy Case Report. [PDF]
Cureus, 2021 Balkan endemic nephropathy (BEN) is a form of interstitial nephritis seen only in certain geographical areas in the Balkan peninsula. Herein we describe the gross and histological changes in a diseased 42-year-old male Caucasian patient with BEN. All the changes fit the classically described alterations, with copper hue discoloration of the skin of the
Stoyanov GS +4 more
europepmc +3 more sources
Expression of Basal Compartment and Superficial Markers in Upper Tract Urothelial Carcinoma Associated with Balkan Endemic Nephropathy, a Worldwide Disease [PDF]
BiomedicinesThe aim of this study was to determine the association of basal compartment and superficial markers, comprising CK5/6, CD44, CK20, and the pathological characteristics of upper tract urothelial carcinoma (UTUC) associated with Balkan endemic nephropathy (
Ljubinka Jankovic Velickovic +5 more
doaj +2 more sources
Simultaneous ipsilateral rhabdoid renal cell carcinoma and multifocal urothelial carcinoma of the ureter in a patient from the region of Balkan endemic nephropathy: Case report and literature review [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2021 Introduction. Simultaneous ipsilateral coexistence of renal cell carcinoma (RCC) and upper urinary tract urothelial carcinoma (UTUC) rarely occurs. Balkan endemic nephropathy (BEN) is a chronic degenerative tubulointerstitial renal disease, strongly ...
Bašić Dragoslav +4 more
doaj +3 more sources
Is Aristolochic Acid Really the Cause of the Balkan Endemic Nephropathy?
Journal of Controversies in Biomedical Research, 2016 In recent years, aristolochic acid has been promoted vigorously as the causal agent of the Balkan endemic nephropathy because of similarities to some other nephropathies, association with DNA adducts and a perception of human exposure via bread. Critical
Peter George Mantle +2 more
doaj +3 more sources
Balkan Endemic Nephropathy Risk Associates to the hs1.2 Ig Enhancer Polymorphism
European Journal of Inflammation, 2012 Balkan Endemic Nephropathy (BEN) is a kidney degenerative disease with a high incidence in the valleys of the Danube and tributary rivers. Many studies describe it as a multifactorial disease.
D. Frezza +11 more
doaj +2 more sources
Balkan endemic nephropathy-current status and future perspectives. [PDF]
Clin Kidney J, 2013 Balkan endemic nephropathy (BEN), originally described in 1956, is a unique familial, chronic renal disease encountered with a high-prevalence rate in Serbia, Bulgaria, Romania, Croatia and Bosnia and Herzegovina. The most prominent features of the disease are its endemic nature, long-incubation period, familial clustering of the disease and an ...
Pavlović NM.
europepmc +4 more sources
Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. [PDF]
PLoS ONE, 2016 TASK-2, a member of the Two-Pore Domain (K2P) subfamily of K+ channels, is encoded by the KCNK5 gene. The channel is expressed primarily in renal epithelial tissues and a potentially deleterious missense variant in KCNK5 has recently been shown to be ...
Alan P Reed +3 more
doaj +2 more sources
Nature of the Virus Associated with Endemic Balkan Nephropathy [PDF]
Emerging Infectious Diseases, 2002 Cristina Riquelme +6 more
doaj +2 more sources
Increased blood pressure in adult offspring of families with Balkan Endemic Nephropathy: a prospective study [PDF]
BMC Nephrology, 2006 Background Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manifest increased blood pressure.
Georgieva Rossitza B +5 more
doaj +2 more sources
Balkan endemic nephropathy: an update on its aetiology. [PDF]
Arch Toxicol, 2016 Stiborová M, Arlt VM, Schmeiser HH.
europepmc +3 more sources